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Nilutamide Coupon - Nilutamide 150mg tablet

nilutamide

Generic Nilandron
Used for Prostate Cancer
Used for Prostate Cancer

Nilutamide (Nilandron) is taken by mouth and used to treat metastatic prostate cancer, meaning cancer that has spread to other parts of the body. It’s a form of hormonal therapy called an androgen receptor inhibitor or antiandrogen, that works to block testosterone in your body. Nilutamide (Nilandron) is one of the recommended options for prostate cancer and is taken once a day. It can cause hot flashes and make it difficult for your eyes to adjust at night, which can be bothersome.

Last reviewed on July 21, 2022
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What is Nilutamide (Nilandron)?

What is Nilutamide (Nilandron) used for?

  • Metastatic prostate cancer

How Nilutamide (Nilandron) works

Most prostate cancer cells need testosterone to grow and spread. Testosterone is a type of male sex hormone called an androgen.

Nilutamide (Nilandron) is an androgen receptor inhibitor (antiandrogen), a type of hormone therapy that works by blocking testosterone from binding to prostate cancer cells. Without testosterone, cancer cells won’t have the “fuel” they need to spread.

Are you looking for information on bicalutamide (Casodex), flutamide (Eulexin), or Xtandi (enzalutamide) instead?

Drug Facts

Common BrandsNilandron
Drug ClassAndrogen receptor inhibitor
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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What are the side effects of Nilutamide (Nilandron)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Side effects experienced by people who took nilutamide (Nilandron) after surgical castration:
  • Hot flashes (28%)
  • Difficulty of eyes adjusting to dark (13%)
  • Nausea (10%)
  • Pain or burning while urinating, needing to urinate more often, and other symptoms of a urinary tract infection (8%)
Side effects experienced by people who took nilutamide (Nilandron) with leuprolide (a LHRH agonist):
  • Hot flashes (67%)
  • Difficulty of eyes adjusting to dark (57%)
  • Nausea (24%)
  • Constipation (20%)
  • Weakness (20%)
  • Shrinking of testicles (16%)
  • Trouble sleeping (16%)
  • Headache (14%)

Other Side Effects

Side effects experienced by people who took nilutamide (Nilandron) after surgical castration:
  • High blood pressure
  • Constipation
  • Higher levels of certain liver enzymes
  • Trouble breathing
  • Dizziness
Side effects experienced by people who took nilutamide (Nilandron) with leuprolide (a LHRH agonist):
  • Loss of appetite
  • Lower sex drive
  • Trouble breathing
  • Stomach pain
  • Larger breast tissue
  • Difficulty of eyes adjusting to light
  • Pain or burning while urinating, needing to urinate more often, and other symptoms of a urinary tract infection

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Severe liver problems: nausea, vomiting, stomach pain, tiredness, loss of appetite, yellowing of the skin or eyes (jaundice), dark urine, right upper stomach pain
  • Serious lung problems: fever, trouble breathing, cough, or chest pain

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Blood in the urine

blurred vision

chest pain

chills

cough

diarrhea

difficult or labored breathing

dizziness

fever or chills

general feeling of discomfort or illness

headache

joint pain

loss of appetite

muscle aches and pains

nausea

nervousness

pale skin

pounding in the ears

runny nose

shivering

shortness of breath

slow or fast heartbeat

sneezing

sore throat

sweating

tightness in the chest

trouble with sleeping

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

vomiting

wheezing

Less common

Arm, back, or jaw pain

blindness

bloody, black, or tarry stools

change in color vision

decreased urine output

decreased vision

difficulty seeing at night

dilated neck veins

fainting

fast or irregular heartbeat

increased cough

increased sensitivity of the eyes to sunlight

irregular breathing

swelling of the face, fingers, feet, or lower legs

vomiting of blood or material that looks like coffee grounds

weight gain or loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acid or sour stomach

belching

body hair loss

bone pain

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

changes in vision

decrease in testicle size

decreased interest in sexual intercourse

depression

difficulty having a bowel movement (stool)

dizziness

dry skin

feeling of warmth

heartburn

inability to have or keep an erection

increased urge to urinate during the night

indigestion

loss in sexual ability, desire, drive, or performance

pain

rash

redness of the face, neck, arms and occasionally, upper chest

sleeplessness

stomach discomfort, upset, or pain

sudden sweating

unable to sleep

waking to urinate at night

Less common

Difficulty with moving

dry mouth

general feeling of discomfort or illness

itching

muscle pain or stiffness

pain, swelling, or redness in the joints

passing of gas

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Nilutamide (Nilandron)

thumbs-up

Pros

Oral pill

Taken once daily

One of the recommended options for metastatic prostate cancer

Available as a lower-cost generic medication

thumbs-down

Cons

Can cause hot flashes, which can be unpleasant

Your eyes might start having problems adjusting to light

Can cause liver or breathing problems

pharmacist-tips

Pharmacist tips for Nilutamide (Nilandron)

pharmacist
  • It’s important to remember to take your dose of nilutamide (Nilandron) each day so you don’t miss a dose. Find a way that works best for you to remember to take your medication. You can also use an app on your phone to help remind you.

    • Nilutamide (Nilandron) can be taken with or without food. It doesn’t matter what time of the day you take it, as long as you take it around the same time each day.

      • Let your provider know immediately if you start to experience new or worsening symptoms of lung problems, like trouble breathing, cough, chest pain, or fever. You might need to stop taking nilutamide (Nilandron) while your provider determines what is causing the problems.

        • After starting nilutamide (Nilandron), you might notice that your eyes have trouble adjusting when you go from a lighted area to a dark area. If this happens, it might take seconds or a few minutes for your eyes to adjust properly. This problem might go away, but sometimes your eyes will continue to have this issue. Wearing tinted glasses can also help. If you notice this problem, your provider might tell you to not drive at night or through tunnels.

          • Ask your healthcare provider or pharmacist about the best way to handle and dispose of this anticancer medication. These medications can be very harmful to people who handle or come into contact with them, so you need to get rid of them safely.

            faqs

            Frequently asked questions about Nilutamide (Nilandron)

            Do I need to get a surgical castration to use nilutamide (Nilandron)?
            Ask your provider if you need a surgical castration with nilutamide (Nilandron). While this medication is approved by the FDA to be used with surgical castration for the treatment of prostate cancer, the National Comprehensive Cancer Network (NCCN) does mention non-surgical alternatives to surgical castration. These alternative options include using medications, such as luteinizing hormone-releasing hormone (LHRH) agonists or LHRH antagonists, for medical castration. The purpose of castration is to stop your body from producing testosterone. While nilutamide (Nilandron) treats prostate cancer by blocking testosterone from triggering the spread of cancer, it doesn’t stop your body from making testosterone. If you already have high levels of testosterone, it can cause nilutamide (Nilandron) to not work as well. Castration (either surgical or medical) is needed to stop your body from making testosterone to help nilutamide (Nilandron) work better.
            How long do I have to take nilutamide (Nilandron) for?
            You should take nilutamide (Nilandron) as long as instructed by your provider. The length of treatment might differ from person to person. It can depend on the type and stage of prostate cancer you have. Typically, you might take nilutamide (Nilandron) for a few weeks or longer. For example, your provider might use nilutamide (Nilandron) to help lower side effects from other prostate cancer medications, such as LHRH agonists. LHRH agonists can cause a temporary side effect called a tumor flare - this is where your testosterone levels rise briefly before falling. During this tumor flare, you might experience symptoms in different parts of your body (only if your tumor has spread to those areas) such as bone pain, trouble urinating, or problems with your spine. In this case, your provider might only continue your nilutamide (Nilandron) for a few weeks during the tumor flare. Ask your provider if you’re not sure how long you need to take this medication for.
            Can I drink alcohol while I take nilutamide (Nilandron)?
            Drinking alcohol while taking nilutamide (Nilandron) should be done with caution. While it’s not known whether alcohol directly interacts with this medication, some people found that nilutamide (Nilandron) made it more difficult for them to tolerate alcohol. In addition, alcohol can worsen some of the side effects of nilutamide (Nilandron), such as hot flashes, dizziness, blurry vision or other vision problems, and nausea. And in more serious cases, drinking alcohol while taking this medication can lead to liver damage. If you experience these symptoms after drinking alcohol, you shouldn’t drink alcohol while taking nilutamide (Nilandron). If you have any questions about taking nilutamide (Nilandron) with alcohol, talk with your provider.
            How do I manage hot flashes from nilutamide (Nilandron)?
            Hot flashes are a very common side effect of nilutamide (Nilandron). Let your provider know if you experience hot flashes while taking nilutamide (Nilandron) and they can suggest ways to help you manage this side effect both with and without medications. Medications that can ease your hot flashes include estrogens, progestin, antidepressants, and anticonvulsants. But these medications can cause additional side effects that you might find bothersome, including nausea, tiredness, or dizziness. If you want to avoid medications, you can try relaxation techniques, breathing exercises, behavioral therapy, and hypnosis, to cope with hot flashes. You can also try wearing loose-fitting clothing or using fans to keep you cool.
            Is nilutamide (Nilandron) better compared with similar medications that treat prostate cancer?
            Nilutamide (Nilandron) isn’t necessarily “better” than other antiandrogen medications, such as bicalutamide (Casodex) or flutamide (Eulexin). But depending on the situation, one medication might be preferred over another. This is because different antiandrogens have different dosing and slightly different side effects. Your provider will help you choose one depending on the type and stage of your prostate cancer, how well your body handles the side effects, other medical conditions you might have, and cost. In some cases, your provider might have you try a different antiandrogen if the medication you started with no longer works well to treat your cancer. Talk with your provider if you have any questions about the benefits and risks for any of the treatment options.
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            What are the risks and warnings for Nilutamide (Nilandron)?

            Nilutamide (Nilandron) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

            risk-warning

            Rare, serious lung condition

            It’s possible for you to develop a rare, but serious lung problem called interstitial pneumonitis when you take nilutamide (Nilandron). This typically happens within the first 3 months after you start nilutamide (Nilandron), but usually goes away after you stop the medication. Your provider might take an x-ray to check your lung health before you start your treatment. And they might monitor your lung health regularly while you’re taking nilutamide (Nilandron). If you do develop lung problems, you'll need to stop this medication. Let your provider know immediately if you experience any symptoms of lung problems, such as new or worsening trouble breathing, cough, chest pain, or fever.

            risk-warning

            Liver injury

            Though rare, it’s possible that nilutamide (Nilandron) can cause you to develop serious liver problems. Typically, problems happen in the first 4 months after you begin the medication. Your provider might monitor your blood levels of certain markers of how well your liver is doing. They might do this before your start nilutamide (Nilandron) and for at least the first 4 months. If you notice yellowing of your skin or eyes, upper right stomach pain, or dark urine, stop nilutamide (Nilandron) and let your healthcare provider know right away because these are symptoms of liver damage.

            dosage

            Nilutamide (Nilandron) dosage forms

            The average cost for 30 tablets of 150mg of Nilutamide (Nilandron) is $1023.59 with a free GoodRx coupon.0
            tablet
            Tablet
            DosageQuantityPrice as low asPrice per unit
            150mg30 tablets$1023.59$34.12

            Typical dosing for Nilutamide (Nilandron)

            The typical starting dose is 300 mg by mouth once a day for 30 days. Then, your provider will lower your dose to 150 mg by mouth once a day.

            interactions

            Interactions between Nilutamide (Nilandron) and other drugs

            Nilutamide (Nilandron) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Nilutamide (Nilandron). Please note that only the generic name of each medication is listed below.

            Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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            How much does Nilutamide (Nilandron) cost?

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            Nilutamide (Nilandron) contraindications

            Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Nilutamide (Nilandron) will not be safe for you to take.
            • Severe liver problems

            • Severe breathing problems

            alternatives

            What are alternatives to Nilutamide (Nilandron)?

            There are a number of medications that your doctor can prescribe in place of Nilutamide (Nilandron). Compare a few possible alternatives below.
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            Nilutamide (Nilandron) images

            White Round Ani 173 - Nilutamide 150mg Tablet
            This medicine is White, Round Tablet Imprinted With "Ani 173".White Round Ani 173 - Nilutamide 150mg Tablet

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