The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Side effects experienced by people who took [[EDITOR|DRUG_DISPLAY_NAME]] after surgical castration:
- Hot flashes (28%)
- Difficulty of eyes adjusting to dark (13%)
- Nausea (10%)
- Pain or burning while urinating, needing to urinate more often, and other symptoms of a urinary tract infection (8%)
Side effects experienced by people who took [[EDITOR|DRUG_DISPLAY_NAME]] with leuprolide (a LHRH agonist):
- Hot flashes (67%)
- Difficulty of eyes adjusting to dark (57%)
- Nausea (24%)
- Constipation (20%)
- Weakness (20%)
- Shrinking of testicles (16%)
- Trouble sleeping (16%)
- Headache (14%)
Less Common Side Effects
Side effects experienced by people who took [[EDITOR|DRUG_DISPLAY_NAME]] after surgical castration:
- High blood pressure
- Constipation
- Higher levels of certain liver enzymes
- Trouble breathing
- Dizziness
Side effects experienced by people who took [[EDITOR|DRUG_DISPLAY_NAME]] with leuprolide (a LHRH agonist):
- Loss of appetite
- Lower sex drive
- Trouble breathing
- Stomach pain
- Larger breast tissue
- Difficulty of eyes adjusting to light
- Pain or burning while urinating, needing to urinate more often, and other symptoms of a urinary tract infection
Nilutamide serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe liver problems: nausea, vomiting, stomach pain, tiredness, loss of appetite, yellowing of the skin or eyes (jaundice), dark urine, right upper stomach pain
- Serious lung problems: fever, trouble breathing, cough, or chest pain
Source: DailyMed
The following Nilutamide side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Blood in the urine
blurred vision
chills
difficult or labored breathing
dizziness
fever or chills
general feeling of discomfort or illness
headache
joint pain
loss of appetite
muscle aches and pains
nervousness
pale skin
pounding in the ears
shivering
shortness of breath
slow or fast heartbeat
sweating
tightness in the chest
trouble with sleeping
troubled breathing with exertion
unusual bleeding or bruising
unusual tiredness or weakness
vomiting
Less common
Arm, back, or jaw pain
blindness
bloody, black, or tarry stools
change in color vision
decreased urine output
decreased vision
difficulty seeing at night
dilated neck veins
fainting
fast or irregular heartbeat
increased cough
increased sensitivity of the eyes to sunlight
irregular breathing
swelling of the face, fingers, feet, or lower legs
vomiting of blood or material that looks like coffee grounds
weight gain or loss
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Acid or sour stomach
belching
body hair loss
bone pain
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
changes in vision
decrease in testicle size
decreased interest in sexual intercourse
difficulty having a bowel movement (stool)
dizziness
feeling of warmth
inability to have or keep an erection
increased urge to urinate during the night
indigestion
loss in sexual ability, desire, drive, or performance
rash
redness of the face, neck, arms and occasionally, upper chest
stomach discomfort, upset, or pain
sudden sweating
unable to sleep
waking to urinate at night
Less common
Difficulty with moving
general feeling of discomfort or illness
muscle pain or stiffness
pain, swelling, or redness in the joints
passing of gas
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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