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Flutamide

Flutamide Side Effects

Lauren Morton, PharmD, BCPSConnie Zheng, PharmD
Reviewed by Lauren Morton, PharmD, BCPS, Connie Zheng, PharmD
Last reviewed on July 20, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Please note: These side effects were experienced by people taking [[EDITOR|DRUG_DISPLAY_NAME]] with a LHRH agonist, and might not be caused by [[EDITOR|DRUG_DISPLAY_NAME]] alone.

Less Common Side Effects

  • Higher blood pressure
  • Drowsiness
  • Confusion
  • Depression
  • Anxiety or nervousness
  • Loss of appetite
  • Swelling of body tissues (i.e., edema)

Flutamide serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious liver problems: nausea, vomiting, stomach pain, tiredness, loss of appetite, yellowing of the skin or eyes (jaundice), dark urine, right upper stomach pain

Source: DailyMed

The following Flutamide side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Black, tarry stools

bloody or cloudy urine

continuing diarrhea

continuing stomach pain

difficult, burning, or painful urination

frequent urge to urinate

pale skin

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

Less common

Blurred vision

chest pain

chills

cough

difficulty with breathing

dizziness

drowsiness

fever

headache

nervousness

pounding in the ears

shortness of breath

slow or fast heartbeat

sore throat

sores, ulcers, or white spots on the lips or in the mouth

swelling

swollen glands

Rare

Abdominal or stomach pain

clay-colored stools

dark urine

general tiredness and weakness

itching

light-colored stools

loss of appetite

nausea and vomiting

rash

tumor

unpleasant breath odor

upper right abdominal pain

vomiting of blood

yellow eyes and skin

Incidence not known

Back, leg, or stomach pains

bleeding gums

blistering, peeling, or loosening of the skin

bluish-colored lips, fingernails, or palms

discoloration of the urine

dizziness or lightheadedness

flushing or redness of the skin

general body swelling

headache

itching

joint or muscle pain

nosebleeds

rapid heart rate

red irritated eyes

red skin lesions, often with a purple center

unusually warm skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Goosebumps

shakiness and unsteady walk

tearing of the eyes

unsteadiness, trembling, or other problems with muscle control or coordination

weight loss

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Decreased interest in sexual intercourse

diarrhea

feeling of warmth

inability to have or keep an erection

indigestion

loss in sexual ability, desire, drive, or performance

passing of gas

redness of the face, neck, arms and occasionally, upper chest

stomach pain, fullness, or discomfort

sudden sweating

swelling of the breasts or breast soreness in both females and males

Less common

Depression

drowsiness

fear or nervousness

mood or mental changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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