The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Hot flashes (53%)
- Whole body pain (35%)
- Back pain (25%)
- Weakness (22%)
- Constipation (22%)
- Pelvic (area below your belly and above your legs) pain (21%)
- Infection (18%)
- Nausea (15%)
- Swelling in arms or legs (13%)
- Difficulty breathing (13%)
- Urinating a lot at night (12%)
- Blood in the urine (12%)
- Diarrhea (12%)
- Stomach pain (11%)
- Dizziness (10%)
Note: These side effects are from people taking [[EDITOR|DRUG_DISPLAY_NAME]] with a LHRH agonist, and might not be from [[EDITOR|DRUG_DISPLAY_NAME]] alone
Less Common Side Effects
- Rash
- Bone pain
- Cough
- Pain while urinating and other symptoms of a urinary tract infection
- Breast enlargement or tenderness
- Feeling of “pins and needles”
- Weight loss
- Heartburn
- Chest pain
- Headache
- Flu-like symptoms
Bicalutamide serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe liver problems: yellowing of the skin or eyes (jaundice), dark urine, right upper stomach pain, nausea, vomiting, tiredness, loss of appetite, chills, fever
- Serious bleeds: bleeding or bruising that doesn’t stop or go away, large amount of bleeding, blood in the urine, throwing up blood, bloody or black and tarry stools
Source: DailyMed
The following Bicalutamide side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Bloating or swelling of the face, arms, hands, lower legs, or feet
blood in the urine
blurred vision
body aches or pain
chills
congestion
cough producing mucus
difficult or labored breathing
dizziness
dryness or soreness of the throat
headache
hoarseness
lower back or side pain
nervousness
painful or difficult urination
pounding in the ears
rapid weight gain
slow or fast heartbeat
sweating
tender, swollen glands in the neck
tightness in the chest
tingling of the hands or feet
trouble with swallowing
unusual weight gain or loss
voice changes
Less common
Abnormal growth filled with fluid or semisolid material
ankle, knee, or great toe joint pain
arm, back, or jaw pain
bleeding from the rectum or bloody stools
blindness
bloody nose
burning feeling while urinating
burning, tingling, numbness, or pain in the hands, arms, feet, or legs
change in bowel habits
chest pain, discomfort, tightness or heaviness
confusion
decrease in frequency of urination
decrease in urine volume
decreased vision
difficulty in passing urine (dribbling)
difficulty with swallowing or eating
dilated neck veins
fainting
irregular breathing or heartbeat
joint stiffness or swelling
lightheadedness
loss of appetite
lump or swelling in the abdomen or stomach
no blood pressure or pulse
noisy breathing
pain or discomfort in the arms, jaw, back, or neck
painful blisters on the trunk of the body
persistent, non-healing sore
rapid, shallow breathing
reddish patch or irritated area
sensation of pins and needles
shiny bump
stabbing pain
stomach discomfort
stopping of the heart
sunken eyes
thirst
tumor
unconsciousness
unexplained weight loss
unusual tiredness or weakness
vomiting
white, yellow, or waxy scar-like area
wrinkled skin
yellow skin or eyes
Incidence not known
Bleeding gums
coughing up blood
hives or welts, itching, skin rash
increased menstrual flow or vaginal bleeding
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
paralysis
prolonged bleeding from cuts
red or black, tarry stools
red or dark brown urine
redness of the skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Belching
breast pain
decreased interest in sexual intercourse
difficulty with moving
hair loss or thinning of the hair
inability to have or keep an erection
indigestion
leg cramps
loss in sexual ability, desire, drive, or performance
loss of strength or energy
muscle ache, cramp, pain, or weakness
pain in the pelvis
pain or tenderness around the eyes and cheekbones
passing of gas
sleepiness or unusual drowsiness
stomach pain or fullness
stuffy or runny nose
swelling of the breasts or breast soreness in both females and males
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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