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Monovisc Coupon - Monovisc 4ml of 22mg/ml syringe

Monovisc

hyaluronic acid
Used for Osteoarthritis
Used for Osteoarthritis

Monovisc (hyaluronic acid) is a viscosupplement that's injected into the knee joint to ease pain from osteoarthritis (OA) in adults. It's usually prescribed for people who continue to have pain despite having tried certain treatments, such as exercises and acetaminophen (Tylenol). Monovisc (hyaluronic acid) given as a single injection by a healthcare professional (HCP). Some potential side effects of this knee injection include joint pain, joint swelling, and injection site pain.

Reviewed by:
reviewer
Kristianne Hannemann, PharmD
reviewer
Connie Zheng, PharmD
Last reviewed on November 5, 2024
BasicsSide effectsPros & consPharmacist tipsFAQsDosageInteractionsCostContraindicationsAlternativesLatest newsImagesReferencesPricesMedicare
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What is Monovisc (hyaluronic acid)?

What is Monovisc (hyaluronic acid) used for?

How Monovisc (hyaluronic acid) works

Monovisc (hyaluronic acid) is a viscosupplement. It's similar to hyaluronic acid, a substance that's naturally found in the connective tissues in your body. When Monovisc (hyaluronic acid) is injected into the knee, it helps lubricate the knee joint so that you can move it smoothly. This can ease pain from osteoarthritis in the knee.

Are you looking for information on Hyalgan (sodium hyaluronate) or GenVisc 850 (sodium hyaluronate) instead?

Drug Facts

Common BrandsMonovisc
Drug ClassViscoelastic
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only
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What are the side effects of Monovisc (hyaluronic acid)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Joint pain (4%)
  • Injection site pain (2%)
  • Joint swelling (1%)

Other Side Effects

  • Joint stiffness
  • Pain in arms or legs
  • Bruise
  • Hard lump under the skin

Source: Prescribing Information

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Difficulty with moving

muscle pain or stiffness

pain in the joints

Less common

Swelling or redness in the joints

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Monovisc (hyaluronic acid)

thumbs-up

Pros

Given as only one injection

Pain relief might last longer than corticosteroids

Good option for people who've tried other treatments that didn't work well

Not made with any animal products

thumbs-down

Cons

Not studied in people younger than 21 years old

Must be given by a healthcare professional

Not a first-choice treatment for OA

Can cause temporary pain and swelling where it's injected

pharmacist-tips

Pharmacist tips for Monovisc (hyaluronic acid)

pharmacist

  • Your prescriber might have you avoid physical activity after receiving Monovisc (hyaluronic acid). In general, take things easy for the first 48 hours right after your injection. You should avoid strenuous activities such as running, jumping, playing tennis, biking or standing on your feet for more than 1 hour at a time. Ask your prescriber when you can continue these physical activities again.

    • You can expect to experience temporary pain and swelling in the knee where Monovisc (hyaluronic acid) was injected. This is typically mild and should go away after 1 to 3 days. But if it doesn't, contact your prescriber.

      • There isn't enough information to know if Monovisc (hyaluronic acid) is safe for you or your baby. If you're pregnant or breastfeeding, talk to your prescriber about the risks and benefits of receiving this knee injection.

        faqs

        Frequently asked questions about Monovisc (hyaluronic acid)

        Does Monovisc (hyaluronic acid) injection hurt?
        Injections like Monovisc (hyaluronic acid) can cause pain at the injection site. But it's typically mild and should go away 1 to 3 days after the injection. If you're concerned about pain, ask your healthcare professional about a numbing medication before getting your injection.
        How long do Monovisc (hyaluronic acid) injections last?
        Everyone responds differently to treatment with Monovisc (hyaluronic acid). Clinical studies have shown that pain relief from Monovisc (hyaluronic acid) can last up to 6 months.
        How long does it take for Monovisc (hyaluronic acid) injection to work?
        You might start noticing pain relief within 1 week of getting Monovisc (hyaluronic acid). But studies show that it can take several weeks to see the full pain-relieving effects.
        What are the side effects of Monovisc (hyaluronic acid) injection?
        The most common side effects reported by people who got Monovisc (hyaluronic acid) during studies are joint pain, joint swelling, and injection site pain. These side effects are usually temporary. But if they persist or seem severe, you should contact your care team.
        Is Monovisc (hyaluronic acid) a steroid?
        No, Monovisc (hyaluronic acid) isn't a steroid. It contains hyaluronic acid, which is a gel-like substance that helps lubricate the joints and helps absorb shock from movements. There are other knee injections used to treat osteoarthritis that do contain a steroid.
        Is Monovisc (hyaluronic acid) a rooster comb injection?
        No, Monovisc (hyaluronic acid) isn't made from rooster combs, the red comb-like structure on top of a rooster's head. Some knee injections that contain sodium hyaluronate are made using rooster combs, which also contains the same gel-like substance that's in our knee joints. But Monovisc (hyaluronic acid) is made from bacterial cells instead, and not with animal products.
        What's the difference between Monovisc (hyaluronic acid) and Synvisc One (hylan G-F 20)?
        Both Monovisc (hyaluronic acid) and Synvisc (hylan G-F 20) are knee injections used to reduce pain due to OA. Both injections are given as a single injection by a healthcare professional (HCP). But there are some differences in the chemical consistency between Monovisc and Synvisc One. In addition, Synvisc is made using rooster combs, while Monovisc (hyaluronic acid) is made from bacteria. Talk to your healthcare professional to find out additional differences between these knee injections.
        Does Monovisc (hyaluronic acid) cause weight gain?
        Weight gain wasn't a side effect reported by people taking Monovisc (hyaluronic acid) during clinical studies. If you have concerns about your weight, contact your primary care provider.
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        dosage

        Monovisc (hyaluronic acid) dosage forms

        Typical dosing for Monovisc (hyaluronic acid)

        Each Monovisc injection contains 88 mg of hyaluronan.

        • Adults age 21 years and older: The typical dose is one injection given into the knee joint by a healthcare professional.

        interactions

        Interactions between Monovisc (hyaluronic acid) and other drugs

        Monovisc (hyaluronic acid) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Monovisc (hyaluronic acid). Please note that only the generic name of each medication is listed below.

        Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

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        How much does Monovisc (hyaluronic acid) cost?

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        Monovisc (hyaluronic acid) contraindications

        Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Monovisc (hyaluronic acid) will not be safe for you to take.

        • Current infection or skin problems in area of injection

        • Known allergy to hyaluronate products

        • Known allergy to gram positive bacteria proteins

        • Bleeding problems

        alternatives

        What are alternatives to Monovisc (hyaluronic acid)?

        There are a number of medications that your doctor can prescribe in place of Monovisc (hyaluronic acid). Compare a few possible alternatives below.
        Monovisc (hyaluronic acid)
        Used for:
        $1488.00 Lowest GoodRx priceView Prices
        Triamcinolone injection (Kenalog)
        Used for:
        $5.03 Lowest GoodRx priceView Prices
        Synvisc (hylan G-F 20)
        Used for:
        View Prices
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        References

        Best studies we found

        American College of Rheumatology. (n.d.). Osteoarthritis guideline.

        Anika Therapeutics, Inc. (2020). Instructions for use: Monovisc™. 

        Foran, J. R. H. (2021). Viscosupplementation treatment for knee arthritis. OrthoInfo. 

        View All References (2)

        McArthur, B. A., et al. (2012). Long term safety, efficacy, and patient acceptability of hyaluronic acid injection in patients with painful osteoarthritis of the knee. Patient Preference and Adherence.

        Peck, J., et al. (2021). A comprehensive review of viscosupplementation in osteoarthritis of the knee. Orthopedic Reviews.

        GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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