The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Dizziness (29%)
- Headache (15%)
- Dry mouth (9%)
- Constipation (7%)
- Nausea (6%)
- Sleep problems (5%)
Less Common Side Effects
- Sleepiness
- Tiredness
- Tremors
- Low blood pressure when standing up
- Anxiety
- Chills
- Sweating
- Diarrhea
Marplan serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Suicidal thoughts or behaviors
- Extremely high blood pressure: seizure, chest pain, severe headache, frequent headaches, confusion, blurry vision, anxiety, trouble breathing
- Serotonin syndrome: hallucinations, seizure, confusion, restlessness, shivering, sweating, high fever, headache, racing heart, muscle stiffness or twitching, tremor
Source: DailyMed
The following Marplan side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chills
cold sweats
confusion
difficult urination
dizziness, faintness, or lightheadedness when getting up from lying or sitting position
fainting
fast, irregular, pounding, or racing heartbeat or pulse
fear or nervousness
heavy feeling
increased need to urinate
passing urine more often
restlessness
shakiness in the legs, arms, hands, or feet
sudden jerky movements of the body
sweating
trembling or shaking of the hands or feet
trouble sitting still
Incidence not known
Agitation
burning while urinating
change in consciousness
decrease in frequency of urination
decrease in urine volume
decreased urine output
difficulty in passing urine (dribbling)
dizziness
false or unusual sense of well-being
headache
hostility
irritability
loss of bladder control
loss of consciousness
muscle twitching
need to keep moving
numbness or tingling of the hands, feet, or face
rapid weight gain
seeing, hearing, or feeling things that are not there
seizures
shakiness and unsteady walk
stupor
swelling of the face, ankles, or hands
unsteadiness, trembling, or other problems with muscle control or coordination
unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Decreased interest in sexual intercourse
drowsiness
inability to have or keep an erection
loss in sexual ability, desire, drive, or performance
relaxed and calm
sleepiness
trouble sleeping
unable to sleep
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
Incidence not known
Black tongue
blurred vision
change in vision
impaired vision
increased sensitivity of the skin to sunlight
raised, dark red, wart-like spots on the skin, especially when used on the face
redness or other discoloration of the skin
severe sunburn
skin rash
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.






