The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
[[EDITOR|DRUG_DISPLAY_NAME|||title]] tablets and capsules:
- Nausea (20%)
- Dizziness (14%)
- Stomach pain (8%)
- Confusion (6%)
- Hallucinations (6%)
- Dry mouth (6%)
Zelapar (selegiline) ODTs:
- Nausea (11%)
- Dizziness (11%)
- General body pain (8%)
- Headache (7%)
- Trouble sleeping (7%)
- Runny nose (7%)
- Involuntary movements (dyskinesia; 6%)
- Skin irritation (6%)
- Back pain (5%)
- Indigestion (5%)
- Inflamed or sore mouth (5%)
- Other irritation in the mouth (e.g., pain when swallowing, pain in mouth, mouth sores)
Less Common Side Effects
[[EDITOR|DRUG_DISPLAY_NAME|||title]] tablets and capsules:
- Headache
- Involuntary movements
- Vivid dreams
- Trouble sleeping
Zelapar (selegine) ODTs:
- Muscle aches
- Tremor or shaking
- Poor coordination
- Sleepiness
- Vomiting
- Constipation
- Dry mouth
- Sore throat
- Shortness of breath
- Rash
- Hallucinations
- High blood pressure
Selegiline serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Extreme drowsiness or falling asleep without warning
- Extremely high blood pressure: seizure, chest pain, severe headache, confusion, blurred vision, anxiety, trouble breathing
- Serotonin syndrome: hallucinations, seizure, confusion, restlessness, shivering, sweating, high fever, headache, racing heart, muscle stiffness or twitching, tremor
- Impulse-control behavior: intense urges (e.g., gambling, shopping, binge eating, engaging in sexual activity)
- Serious withdrawal symptoms (neuroleptic malignant syndrome): high fever, sweating, stiff muscles, confusion, not aware of your surroundings, fast or irregular heartbeat
Source: DailyMed
The following Selegiline side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
Less common
Blurred vision
bruising
convulsions
decreased urine
difficult or labored breathing
difficulty with swallowing
discouragement
dizziness
feeling sad or empty
headache
increased thirst
irregular heartbeat
irritability
large, flat, blue or purplish patches in the skin
loss of appetite
loss of interest or pleasure
mood changes
muscle pain or cramps
nausea or vomiting
nervousness
numbness or tingling in the hands, feet, or lips
pounding in the ears
seeing, hearing, or feeling things that are not there
shakiness and unsteady walk
shakiness in the legs, arms, hands, or feet
sleepiness or unusual drowsiness
slow or fast heartbeat
swelling or inflammation of the mouth
tightness in the chest
tiredness
trouble concentrating
trouble sleeping
unsteadiness, trembling, or other problems with muscle control or coordination
unusual tiredness or weakness
Get emergency help immediately if any of the following symptoms of overdose occur:
Symptoms of overdose
Agitation
difficulty opening the mouth or lockjaw
dizziness (severe) or fainting
fast or irregular pulse (continuing)
high fever
high or low blood pressure
severe spasm where the head and heels are bent backward and the body arched forward
troubled breathing
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Acid or sour stomach
back pain
belching
bloated or full feeling
body aches or pain
congestion
difficulty having a bowel movement (stool)
difficulty with moving
dryness or soreness of the throat
excess air or gas in the stomach or intestines
hoarseness
indigestion
joint pain
leg cramps
muscle aching or cramping
muscle pains or stiffness
passing gas
stomach discomfort, upset, or pain
swollen joints
tender, swollen glands in the neck
tooth problems
voice changes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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