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Rasagiline

Rasagiline Side Effects

Ashley Wong, PharmDCydnee Ng, PharmD
Reviewed by Ashley Wong, PharmD, Cydnee Ng, PharmD
Last reviewed on December 1, 2021

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache (14%)
  • Joint pain (7%)
  • Stomach upset (7%)
  • Depression (5%)
  • Flu symptoms (5%)
  • Falls (5%)

Note: Percentages are based on taking the medication alone

Less Common Side Effects

  • Pink eye
  • Fever
  • Stomach flu
  • Runny nose

Rasagiline serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serotonin syndrome: Hallucinations, coma, seizures, confusion, restlessness, fainting, shivering, sweating, high fevers, headache, racing heart, high blood pressure, diarrhea, muscle stiffness or twitching, tremor
  • Neuroleptic malignant syndrome (NMS): Very high fevers, confusion, irregular pulse, sweating, muscle stiffness, changes in blood pressure
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Source: DailyMed

The following Rasagiline side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Abdominal or stomach pain

arm, back, or jaw pain

black, tarry stools

chest pain or discomfort

chest tightness or heaviness

chills

cloudy urine

cough

diarrhea

difficulty swallowing

dizziness

fainting

fast or irregular heartbeat

fever

hives, itching, or skin rash

loss of appetite

nausea

painful or difficult urination

persistent, non-healing sore

pink growth on the skin

puffiness or swelling of the eyelids or around the eyes

reddish patch or irritated area

redness, blistering, peeling, or loosening of the skin

seeing, hearing, or feeling things that are not there

shiny bump

sore throat

sores, ulcers, or white spots on lips or in mouth

sweating

swollen glands

tests that show problems with the liver

tightness in the chest

unusual bleeding or bruising

unusual tiredness or weakness

weakness

white, yellow or waxy scar-like area

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Acid or sour stomach

belching

difficulty with moving

headache

heartburn

indigestion

muscle pain or stiffness

pain in the joints

stomach discomfort or upset

Less common

Bruising

burning, crawling, itching, numbness, prickling, "pins and needles" or tingling feelings

burning, dry, or itching eyes

decreased interest in sexual intercourse

difficulty breathing

difficulty with moving

discouragement

excessive tearing

eye discharge

fall

feeling of constant movement of self or surroundings

feeling sad or empty

general feeling of discomfort or illness

hair loss

inability to have or keep an erection

irritability

joint pain

lack of appetite

large, flat, blue or purplish patches in the skin

lightheadedness

loss in sexual ability, desire, drive, or performance

loss of interest or pleasure

muscle aches

neck pain

noisy breathing

redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid

runny nose

sensation of spinning

shivering

sneezing

stuffy nose

swelling or redness in the joints

thinning of the hair

tiredness

trouble concentrating

trouble sleeping

vomiting

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Ashley Wong, PharmD, is a licensed pharmacist in California. She has over 6 years of experience providing drug information.
Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.

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