Junel Fe 24 is a birth control pill that's taken every day to prevent pregnancy. As a combined oral contraceptive (COC), the active pills contain 2 hormones: norethindrone (a progestin) and ethinyl estradiol (an estrogen), while the inactive pills have some iron. It has a lower estrogen dose and 24 active tablets, compared to the usual 21 in similar COCs. Junel Fe 24 is a monophasic birth control, meaning all active tablets have the same hormone levels. Common side effects include headache, nausea, and weight gain.
Junel Fe 24 is a generic of the discontinued brand name Loestrin 24 Fe. Other generics like Junel Fe 24 include Aurovela 24 fe, Blisovi 24 Fe, Hailey 24 Fe.
To prevent pregnancy
Junel Fe 24 is a combination medication that contains two hormones: norethindrone (a progestin) and ethinyl estradiol (an estrogen). These hormones work together to prevent pregnancy by:
Stopping ovulation (release of an egg from the ovary)
Changing cervical mucus to block sperm movement
Changing the lining of the uterus so it's more difficult for a fertilized egg to implant
Junel Fe 24 also contains inactive (hormone-free) tablets with ferrous fumarate. This iron supplement is added to reduce your risk of anemia during the days you’re taking the inactive tablets and may experience bleeding.
Source: DailyMed
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
Taken once daily with or without food
Works well to prevent pregnancy
Inactive pills contain iron, which might lower your risk for anemia
Raises the risk of a blood clot
Raises the risk of liver problems
Instructions for missed doses vary by week and number of doses missed
Set an alarm for the same time every day to help you remember to take Junel Fe 24. The chance of accidentally getting pregnant gets higher if you forget to take a pill while you're sexually active.
Junel Fe 24 doesn't protect you against human immunodeficiency virus (HIV) or other sexually transmitted infections (STIs). Be sure to use a condom during sex to lower your risk of getting HIV and other STIs.
Let your OB-GYN provider or pharmacist know all of your current medications. Certain medications like rifampin (Rifadin), can interact with Junel Fe 24 and make it work less well to prevent pregnancy. And you might need to use a back-up method of birth control.
If you start Junel Fe 24 on the first Sunday after your period, use a back-up method of birth control for 7 days because its pregnancy-prevention effects haven't fully kicked in yet. But if you start Junel Fe 24 on the first day of your period, you won't need to use a back-up birth control.
If you want to start Junel Fe 24 after having a baby, check with your OB-GYN provider first. You need to wait at least 4 weeks after delivering your baby before you can start this medication. Starting any earlier raises your risk of blood clots.
If you vomit or have diarrhea within 3 to 4 hours after taking Junel Fe 24, take another active tablet from your pack. If these symptoms last more than 1 day, the medication might not work as well to prevent pregnancy. So it's recommended to use another form of birth control, like condoms or spermicides, until you speak with your OB-GYN.
Wear sunscreen and avoid tanning beds to protect your skin while you're taking Junel Fe 24. This medication can cause some areas of the face, such as the forehead, nose, and cheeks, to darken. Exposure to ultraviolet (UV) rays can darken these areas of skin even more.
Speak to your OB-GYN provider before starting Junel Fe 24 if you're breastfeeding. This medication can lower your milk supply so you might need to consider another form of birth control.
Junel Fe 24 can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factors: Over 35 years old who smoke cigarettes
If you smoke cigarettes, using combined oral contraceptives (COCs), like Junel Fe 24, raises your risk for blood clots. These blood clots can lead to more serious problems, such as heart attack and stroke. People aged 35 years and older who smoke are at even higher risk for these problems. If you smoke, talk with your OB-GYN provider about safer birth control alternatives.
Risk factors: Age 35 or older and smoke | Recent surgery with a long period of bed rest | Starting Junel Fe 24 less than a month after childbirth | High blood pressure | People identified as obese | High cholesterol | Diabetes | Higher dose of estrogen
Junel Fe 24 raises your risk of blood clots. These clots can occur anywhere in your body, including your lungs (pulmonary embolism or PE), legs (deep vein thrombosis or DVT), brain (stroke), and heart (heart attack). Get emergency help right away if you have any signs of a blood clot.
Brain: weakness or numbness in your arms, legs, or face on one side of the body, trouble speaking, blurred vision, dizziness, loss of balance, trouble walking, or confusion
Eyes: trouble seeing, bulging eye, double vision
Heart: chest pain, sweating, nausea, or dizziness
Lungs: trouble breathing, chest pain, or cough
Legs: cramps, swelling, pain, or muscle tightness
If you need to have surgery, tell your care team you're taking Junel Fe 24. They might have you stop taking it 4 weeks before until 2 weeks after your surgery to lower your risk of blood clots. If you recently delivered a baby, you shouldn't start Junel Fe 24 until 4 weeks after delivery if you're not breastfeeding your child.
Risk factors: History of liver problems | Taking certain hepatitis C combination medications
Don't take Junel Fe 24 if you have liver problems. Although rare, COCs like Junel Fe 24 can raise your risk of benign liver tumors. Signs of liver problems can include jaundice (yellowing of the skin or eyes), along with fever, tiredness, loss of appetite, or dark colored urine.
Risk factors: Older age | Taking COCs for a long time
Junel Fe 24 can raise your blood pressure, so you might want to check your blood pressure while you're taking this medication. The risk is higher in older adults that have taken birth control for a long time. Stop taking Junel Fe 24 and let your care team know if your blood pressure is unusually high.
Risk factors: Prediabetes or diabetes | History of high triglycerides
Junel Fe 24 can raise your blood sugar and triglyceride (fat) levels. If you have diabetes or prediabetes, let your prescriber know if you experience any changes in your blood sugar. A rise in triglycerides can lead to serious conditions like inflammation of the pancreas (pancreatitis). Get emergency medical help if you notice symptoms of pancreatitis, which can include stomach pain, nausea, or vomiting.
Let your HCP know if you experience new or worsening migraines or headaches while taking Junel Fe 24. You'll have to stop this medication if your migraine or headache doesn't go away or becomes severe.
People who take Junel Fe 24 can sometimes experience breakthrough bleeding and spotting, especially during the first 3 months of taking this medication. Irregular bleeding can vary from slight staining to bleeding similar to a regular period. This problem might be temporary, so continue taking your medication as directed. Let your OB-GYN provider know if the bleeding is a problem for you. If you missed your period(s), contact your OB-GYN provider or get a pregnancy test to make sure you're not pregnant.
Talk to your OB-GYN provider if you experience symptoms of depression or worsening depression while taking Junel Fe 24. Your prescriber might consider stopping this medication if you have serious depression.
Risk factors: History of breast or cervical cancer | Taking COCs for a long time
Study results are mixed, but there's a possibility that Junel Fe 24 and other COCs can raise your risk for breast and cervical cancer.
Don't take Junel Fe 24 if you currently have or have had breast cancer because some types of breast cancer grow faster in the presence of estrogen, an ingredient in this medication. You can perform breast self-checks regularly at home and get yearly breast exams with your HCP to help with early breast cancer detection. Let your HCP know if you notice any new or abnormal lumps, pain, or swelling in your breasts.
Make sure you follow up with your OB-GYN provider to get proper screenings for cervical cancer. Report any signs of vaginal bleeding or discharge that's not normal.
Risk factors: History of hereditary angioedema | History of chloasma gravidarum
If you have certain conditions, such as hereditary angioedema or chloasma (a skin condition that causes dark patches on the face), talk to your healthcare professional before taking Junel Fe 24 because it might worsen your symptoms. If you have a history of chloasma, limit exposure to the sun or UV light while taking birth control pills like Junel Fe 24.
Dosage | Quantity | Price as low as | Price per unit |
---|---|---|---|
28 tablets of 1mg/20mcg | 3 packages | $35.17 | $11.72 |
Junel Fe 24 (and other branded generics) comes in a 28-day pack. Your medication might look different depending on which branded generic your healthcare professional (HCP) prescribes. Follow your HCP's instructions or the directions on the package when taking it.
There are 24 active tablets containing 1 mg norethindrone acetate and 20 mcg ethinyl estradiol. There are 4 placebo tablets and each contain 75 mg of ferrous fumarate.
The typical dose is to take 1 active tablet by mouth daily for 24 days, followed by 1 placebo tablet daily for the remaining 4 days.
Over 35 years old who smoke
Currently have or have had a blood clot
Blood clotting condition
Certain heart rhythm problems, like atrial fibrillation (AFib)
High blood pressure that's not under control
Diabetes with high blood pressure or organ damage
Any migraine headaches for those over 35 years old
Liver problems or liver disease
Unexplained vaginal bleeding that hasn't been diagnosed
Currently have or have had breast cancer
Take hepatitis C combination medications containing ombitasvir/paritaprevir/ritonavir
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Teva Pharmaceuticals USA, Inc. (2024). Junel Fe 24- norethindrone acetate and ethinyl estradiol and ferrous fumarate kit [package insert]. DailyMed.
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