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Timolol Coupon - Timolol 5ml of 0.5% eye dropper

timolol

Generic Istalol
Used for Glaucoma, Eye Pressure
Used for Glaucoma, Eye Pressure

Istalol (timolol) is an eye drop that's used to lower pressure within the eye and treat glaucoma. It belongs to the beta blocker drug class. This medication can be used by itself or together with other eye drops that aren't beta blockers. Istalol (timolol) is longer-acting than other timolol products, so the usual dosage is once daily in the morning. Common side effects include burning or stinging after you put in the eye drops, but it's generally a temporary feeling.

Last reviewed on February 4, 2024
basics-icon

What is Istalol (timolol)?

What is Istalol (timolol) used for?

  • High pressure in the eye caused by ocular hypertension (high pressure inside the eye) or open-angle glaucoma (the most common type of glaucoma)

How Istalol (timolol) works

Istalol (timolol) is a beta blocker that lowers the amount of fluid in the eye. When there's less fluid inside the eye, the eye pressure goes down.

Drug Facts

Common BrandsIstalol
Drug ClassBeta blocker
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$42.230
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$42.23
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What are the side effects of Istalol (timolol)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Temporary burning or stinging in the eye after using (38%)

Other Side Effects

  • Blurred vision
  • Cataract
  • Eye infection
  • Itchy eye
  • Vision not as sharp
  • Headache
  • High blood pressure

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Trouble breathing: shortness of breath, wheezing, chest tightness
  • Heart failure: shortness of breath; fatigue; swelling in the legs, ankles and feet
  • Allergic reactions: rash around your eyes or face, closing of the throat, hives, swelling

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Chest pain or discomfort

lightheadedness, dizziness, or fainting

shortness of breath

slow or irregular heartbeat

unusual tiredness

Less common

Difficult or labored breathing

fast heartbeat

tightness in chest

wheezing

Rare

Noisy breathing

small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope

swelling of hands, ankles, feet, or lower legs

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Blurred vision

continuing ringing or buzzing or other unexplained noise in ears

headache

hearing loss

nervousness

pounding in the ears

sweating

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Itching skin

red, sore eyes

Rare

Acid or sour stomach

belching

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

decreased interest in sexual intercourse

feeling of constant movement of self or surroundings

heartburn

inability to have or keep an erection

indigestion

lack or loss of strength

loss in sexual ability, desire, drive, or performance

nausea

sensation of spinning

stomach discomfort, upset, or pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Istalol (timolol)

thumbs-up

Pros

Works well to treat high eye pressure

Used only once daily

Lower-cost generic available

thumbs-down

Cons

Unknown if safe for use in children

Might cause more side effects than some other timolol eye medications

pharmacist-tips

Pharmacist tips for Istalol (timolol)

pharmacist
  • Wash your hands before placing Istalol (timolol) drops in your eyes. Avoid touching the dropper tip to your eye or any other surface. Don't touch the dropper tip with your hands. This helps prevent the eye drop solution from getting contaminated with germs and lower the risk for eye infections.

    • If you wear contact lenses, remove them before you place Istalol (timolol) into your eye(s). Wait 15 minutes before putting your lenses back in your eye(s).

      • After placing a drop of Istalol (timolol) in your eye, close your eye and gently press one finger to the inner corner of your eye by the nose for 1 minute. This helps your eye absorb the medication.

        • If you need to use Istalol (timolol) along with other eye drops or ointments, wait 5 minutes between using each product to give your eyes time to absorb each medication.

          • It's not easy to tell whether your eye pressure is improving at home. Use Istalol (timolol) as prescribed, even if you don't notice any differences in your symptoms or vision right away.

            faqs

            Frequently asked questions about Istalol (timolol)

            How long should you use Istalol (timolol) eye drops?
            You'll need treatment for glaucoma with medications like Istalol (timolol) long term, or for as long as the pressure in your eye is still too high. Often, you'll need to continue using Istalol (timolol) every day even if your eye pressure improves so that it stays this way (as long as you're not having bothersome side effects). You'll have eye exams done every so often so your optometrist or ophthalmologist can keep checking your eye pressure.
            Does Istalol (timolol) need to be refrigerated?
            You don't need to refrigerate Istalol (timolol). It's best to keep the medication at room temperature. Never freeze Istalol (timolol) because this could damage the medication.
            Is Istalol the same as timolol?
            Istalol is a longer-acting, brand-name version of timolol maleate eye drops. It comes as a more concentrated strength, 0.5%, which contains about 5 mg of timolol per mL. There's a less concentrated version of timolol (e.g., 0.25%), which your provider might recommend for you if you're having a lot of bothersome side effects with the 0.5% strength. Note that timolol is also available as tablets that are taken by mouth and are used for treating high blood pressure and heart attack and for preventing migraines.
            Can Istalol (timolol) eye drops lower blood pressure and heart rate?
            When it's used as an eye drop, Istalol (timolol) mainly lowers the pressure in your eyes. But it's possible for some of the medication to absorb into your bloodstream and affect other areas of the body like the heart. If this happens, the medication might lower your blood pressure. In addition, low heart rate is another common side effect of timolol tablets (which are taken by mouth). So it's possible that the eye drops can also lower heart rate. Tell your primary care provider if you notice dizziness or a slower heart rate and it bothers you or makes it harder for you to do normal daily activities.
            Can Istalol (timolol) cause hair loss?
            Hair loss isn't a commonly reported side effect of Istalol (timolol), but some people who use timolol eye drops have reported it. Tell your primary care provider about any new or worsening hair loss after you start using Istalol (timolol). They might want to ask you questions to see whether there are other possible causes for your hair loss before recommending a treatment option for you or before switching you to a different eye pressure-lowering medication.
            What's the difference between Istalol (timolol) and other timolol products?
            There are a few different eye products that contain timolol as the only active ingredient and they can all lower pressure in the eyes. The main difference is that Istalol (timolol) is also made with a form of potassium as an inactive ingredient that helps the medication's effect in the eye(s) and allows it to be used once daily. Istalol (timolol) works just as well as shorter-acting timolol eye drops that are typically used twice daily. Talk to your optometrist or ophthalmologist if you're unsure which timolol eye medication you have and whether it best fits your needs.
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            What are the risks and warnings for Istalol (timolol)?

            Istalol (timolol) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

            risk-warning

            Higher risk for heart failure

            • Risk factors: Congestive heart failure | Second- or third-degree heart block

              In rare cases, some people developed heart failure while they used beta-blocking medications like Istalol (timolol). People who already have heart failure might be at risk for worsening heart problems with this medication. Tell your healthcare team about your medical history. And talk to your primary care provider if you notice swelling in your feet or ankles, a fast or irregular pulse, or shortness of breath when you lie down or exercise. These might be signs of heart problems.

              risk-warning

              Not recommended for people with breathing problems

              • Risk factors: History of asthma | History of chronic obstructive pulmonary disease (COPD) | History of other lung problems

                Beta blocker medications like Istalol (timolol) usually aren't recommended for people with lung problems, like asthma and COPD. This is because beta blockers can cause the airways to become narrower, which can make it harder to breathe. But the risk for breathing problems specifically with Istalol (timolol) isn't well known. Make sure your healthcare team knows if you have or have ever had any lung problems or conditions before you start using this medication to check whether it's safe for you.

                risk-warning

                Hidden symptoms of low blood sugar

                • Risk factors: Diabetes

                  Beta blockers can cause people with diabetes to not notice symptoms of low blood sugar, except for sweating and dizziness. It's possible for some Istalol (timolol) to be absorbed into your bloodstream and cause this effect. So though rare, it's important to be aware of this risk. Talk to your primary care provider to see whether you should check your blood sugar more often if you're using Istalol (timolol).

                  risk-warning

                  Hidden symptoms of overactive thyroid

                  Beta blockers can cause people with an overactive thyroid to not recognize the signs of hyperthyroidism, such as a fast heart rate. It's possible for some Istalol (timolol) to get absorbed into your bloodstream and cause this effect. Although rare, it's good to be aware of this risk. Make sure your primary care provider knows that you're using Istalol (timolol) so they can monitor your thyroid problem more closely.

                  risk-warning

                  Worsening of myasthenia gravis

                  In some rare cases, Istalol (timolol) can worsen symptoms like muscle weakness in people who have myasthenia gravis. Watch out for worsening symptoms if you have myasthenia gravis and let your care team know if this happens to you.

                  dosage

                  Istalol (timolol) dosage forms

                  The average cost for 1 eye dropper of 5ml of 0.5% of Istalol (timolol) is $402.37 with a free GoodRx coupon. This is 22.87% off the average retail price of $521.70.
                  eye dropper
                  Eye dropper
                  DosageQuantityPrice as low asPrice per unit
                  2.5ml of 0.5%1 eye dropper$205.88$205.88
                  5ml of 0.5%1 eye dropper$402.37$402.37

                  Typical dosing for Istalol (timolol)

                  The typical dose is 1 drop in the affected eye(s) once daily in the morning.

                  interactions

                  Interactions between Istalol (timolol) and other drugs

                  Istalol (timolol) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Istalol (timolol). Please note that only the generic name of each medication is listed below.

                  Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                  Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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                  How much does Istalol (timolol) cost?

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                  contraindications-icon

                  Istalol (timolol) contraindications

                  Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Istalol (timolol) will not be safe for you to take.
                  alternatives

                  What are alternatives to Istalol (timolol)?

                  There are a number of medications that your doctor can prescribe in place of Istalol (timolol). Compare a few possible alternatives below.
                  Istalol (timolol)
                  Used for:
                  • High pressure in the eye caused by ocular hypertension (high pressure inside the eye) or open-angle glaucoma (the most common type of glaucoma)

                  $42.23 Lowest GoodRx priceView Prices
                  Used for:
                  • High pressure in the eye caused by ocular hypertension (high pressure inside the eye) or open-angle glaucoma (the most common type of glaucoma)

                  $44.86 Lowest GoodRx priceView Prices
                  Used for:
                  • High pressure in the eye caused by ocular hypertension (high blood pressure inside the eye) or open-angle glaucoma (the most common type of glaucoma)

                  $28.26 Lowest GoodRx priceView Prices
                  images

                  Istalol (timolol) images

                  yellow - Timolol Maleate 0.5% Ophthalmic Solution
                  This medicine is Yellow Eye Dropper.yellow - Timolol Maleate 0.5% Ophthalmic Solution
                  This medicine is Colorless Eye Dropper.
                  This medicine is Colorless Eye Dropper.
                  colorless - Timolol Maleate 0.5% Ophthalmic Solution
                  This medicine is Colorless Eye Dropper.colorless - Timolol Maleate 0.5% Ophthalmic Solution
                  colorless - Timolol Hemihydrate 0.5% Ophthalmic Solution
                  This medicine is Colorless Eye Dropper.colorless - Timolol Hemihydrate 0.5% Ophthalmic Solution
                  colorless - Timolol Maleate 0.5% Ophthalmic Solution
                  This medicine is Colorless Eye Dropper.colorless - Timolol Maleate 0.5% Ophthalmic Solution
                  colorless - Timolol Maleate 0.5% Ophthalmic Solution
                  This medicine is Colorless Eye Dropper.colorless - Timolol Maleate 0.5% Ophthalmic Solution
                  yellow - Timolol Maleate 0.5% Ophthalmic Solution (Once-Daily)
                  This medicine is Yellow Eye Dropper.yellow - Timolol Maleate 0.5% Ophthalmic Solution (Once-Daily)
                  yellow - Timolol Maleate 0.5% Ophthalmic Solution
                  This medicine is Yellow Eye Dropper.yellow - Timolol Maleate 0.5% Ophthalmic Solution

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                  References

                  Best studies we found

                  American Optometric Association. (n.d.). Ocular hypertension.

                  Bausch & Lomb Incorporated. (2022). Istalol- timolol maleate solution/ drops [package insert]. DailyMed.

                  Hafeez, Y., et al. (2023). Sinus bradycardia. StatPearls.

                  View All References (8)
                  GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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