The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Darkening or discoloration of the skin (58%)
- Nausea (55%)
- Vomiting (38%)
- Headache (37%)
- Moles (new, larger, or darker ones; 15%)
- Constipation (12%)
- Dizziness (12%)
- Mouth or throat pain (11%)
Less Common Side Effects
- Other stomach upset
- Unplanned erections or more frequent erections
- Adrenal insufficiency
- Ear infection
- Injection site reaction (e.g., redness, itchiness, swelling, pain, bruising)
Note: Side effects were from people 4 years and older with acquired HO. Side effects might differ for those with BBS, or POMC, PCSK1, or LEPR deficiency.
Imcivree serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Depression: feeling sad or hopeless, feeling less interested than usual in activities that you typically enjoy, low energy
- Suicidal thoughts and behavior
- Problems with sexual function: unexpected erections, erections lasting longer than 4 hours, unwanted sexual arousal
- Serious allergic reaction: trouble breathing; trouble swallowing; fast heartbeat; swelling of your face, lips, tongue, or throat
When do Imcivree possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Injection site reactions
Nausea or vomiting
Darker skin
Risk of depression
Risk of suicidal thoughts
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.
Source: Prescribing information
The following Imcivree side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- High sodium level—confusion, increased thirst, muscle weakness, unusual weakness or fatigue, twitching muscles
- Low adrenal gland function—nausea, vomiting, loss of appetite, unusual weakness or fatigue, dizziness
- Low sodium level—muscle weakness, fatigue, dizziness, headache, confusion
- Prolonged or painful erection
- Thoughts of suicide or self-harm, worsening mood, feelings of depression
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
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