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Vyleesi

Vyleesi Side Effects

Cydnee Ng, PharmDKristianne Hannemann, PharmD
Reviewed by Cydnee Ng, PharmD, Kristianne Hannemann, PharmD
Last reviewed on May 30, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea (40%)
  • Flushing of the skin (20%)
  • Injection site reactions (e.g., pain, redness, itching, bruising; 13%)
  • Headache (11%)

Less Common Side Effects

  • Vomiting
  • Tiredness
  • Dizziness
  • "Pins and needles" feeling in the arms and legs
  • Hot flush
  • Cough
  • Stuffy nose
When do Vyleesi possible side effects begin and end?
Time passed since treatment started:
M
H
D
W
M
Nausea
Flushing
Slower heartbeat
Higher blood pressure
Injection site reactions

Source: DailyMed

The following Vyleesi side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Change in skin color
  • Increase in blood pressure
  • Slow heartbeat—dizziness, feeling faint or lightheaded, confusion, trouble breathing, unusual weakness or fatigue

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

  • Fatigue
  • Flushing
  • Headache
  • Nausea
  • Pain, redness, irritation, or bruising at the injection site
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