Endometrin

Endometrin Side Effects

Reviewed by Allison Gourley, PharmD, Cydnee Ng, PharmD

Last reviewed on July 25, 2024

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Pain after egg retrieval (e.g., pelvic pain, stomach cramps; 25-28%)
Stomach pain (12%)
Nausea (7-8%)
Ovarian hyperstimulation syndrome (swollen ovaries; 7%)

Less Common Side Effects

Stomach bloating
Vomiting
Constipation
Fatigue
Headache
Vaginal irritation
Vaginal burning
Vaginal discharge

Endometrin serious side effects

Contact your healthcare provider immediately if you experience any of the following.

Blood clot(s): pain in the lower leg that won't go away, sudden shortness of breath, coughing up blood, sudden blindness
Heart attack: chest pain or tightness; pain that travels to your shoulder, arm, neck, or jaw
Stroke: sudden trouble talking or walking; numbness on one side of your body or face; sudden, severe headaches
Abnormal vaginal bleeding

Source: DailyMed

The following Endometrin side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Chest pain

chills

cold or flu-like symptoms

cough or hoarseness

fever

problems with urination

Less common

Clear or bloody discharge from the nipple

dimpling of the breast skin

inverted nipple

lump in the breast or under the arm

persistent crusting or scaling of the nipple

redness or swelling of the breast

sore on the skin of the breast that does not heal

Incidence not known

Abdominal or stomach pain

bloating

blurred vision

change in vaginal discharge

clay-colored stools

cleft lip or palate

confusion

constipation

darkened urine

diarrhea

difficult or labored breathing

difficulty with swallowing

difficulty with walking

dizziness

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

fainting

fast, pounding, or irregular heartbeat or pulse

headache

hives

indigestion

irregular heartbeat

irritation

itching

joint pain, stiffness, or swelling

lightheadedness

loss of appetite

nausea

nervousness

noisy breathing

numbness or tingling in the face, arms, or legs

pain or feeling of pressure in the pelvis

pains in the stomach, side, or abdomen, possibly radiating to the back

pounding in the ears

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rash

redness of the skin

shortness of breath

slow heartbeat

spontaneous abortion

stomach or pelvic discomfort, aching, or heaviness

sweating

swelling of the eyelids, face, lips, hands, or feet

tightness in the chest

trouble speaking, thinking, or walking

unpleasant breath odor

unusual tiredness or weakness

vaginal bleeding

vomiting

vomiting of blood

wheezing

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Breast pain or tenderness

depression

muscle or joint pain

white or brownish vaginal discharge

worry

Incidence not known

Attack, assault, or force

blurred or loss of vision

change in walking and balance

changes in behavior

changes in patterns and rhythms of speech