Key takeaways:
Progesterone comes in several prescription forms, including capsules (Prometrium), an injection, and vaginal inserts (Endometrin) or gel (Crinone). All forms of progesterone, except Crinone, are available as lower-cost generics.
Without insurance, the average cash price of 30 progesterone 100 mg capsules is $49.14. But you could pay as little as $15.00 for the same prescription with a free GoodRx discount.
Choosing a lower-cost generic and using GoodRx discounts may help lower your out-of-pocket costs for progesterone. A manufacturer savings card is also available for brand-name Crinone.
Save on related medications
Progesterone is a prescription medication that comes in several forms. These include oral capsules (Prometrium), an oil for injection, and vaginal inserts (Endometrin) or gel (Crinone). Progesterone is often prescribed for hormone-related conditions or as part of fertility treatments. But how much does it cost?
The cost of progesterone depends on the form you’re prescribed and whether you have insurance coverage, among other factors. Read on to learn more about how much progesterone costs without insurance and ways to save on the cost of your prescription.
How much does progesterone cost without insurance?
The average cash price of 30 progesterone 100 mg capsules is $15.00. But prices can vary between brand-name and generic products, as well as between different dosage forms.
The chart below shows placeholder average cash prices for common progesterone forms, doses, and quantities.
Progesterone dose, form, and quantity | Brand-name average cash price | Generic average cash price |
|---|---|---|
Prometrium 100 mg, 30 capsules | ||
Prometrium 200 mg, 30 capsules | ||
Progesterone in oil 50 mg/mL injection 10 mL, 3 vials | N/A | |
Endometrin 100 mg, 21 vaginal inserts | ||
Crinone 8% vaginal gel, 15 applicators | N/A |
Which factors affect the cost of progesterone?
The cost of progesterone can vary based on several factors.
Brand vs. generic availability
Generic medications typically cost less than their brand-name counterparts.
Oral progesterone capsules, injectable progesterone in oil, and Endometrin vaginal inserts come as lower-cost generics. But Crinone vaginal gel is a brand-name-only medication.
Dose, form, and quantity
Your progesterone dose, form, and quantity can also affect your cost. For example, progesterone 100 mg capsules are typically more affordable than 200 mg capsules. Oral and injectable forms of progesterone typically cost less than vaginal inserts or gel.
Location
Where you live can affect the cost of your prescription medications. For example, according to GoodRx research, people in Little Rock tend to pay more for prescription medications than people in Houston.
Pharmacy
Pharmacies negotiate their own pricing for prescription medications. So the cash price of progesterone can vary among different pharmacies, even if they’re located in the same neighborhood. GoodRx can help you compare prices among pharmacies in your area to help you find the lowest price.
Insurance coverage
If you have prescription insurance, it may lower what you pay for progesterone. But you may still have out-of-pocket costs, such as a deductible, copay, or coinsurance.
What you pay can depend on whether your progesterone product is on your plan’s formulary (list of covered medications) and what tier it falls under. You can check your coverage details in your plan’s summary of benefits and coverage online or by calling the number on the back of your prescription insurance card.
What to do if progesterone isn’t covered by your insurance
Your prescription insurance may not cover certain progesterone products. This is common with products used as part of fertility treatment, since not all plans include coverage for infertility. If your insurance doesn’t cover progesterone, try these options:
Ask your prescriber to submit a letter of medical necessity or request a formulary exception. If that request is denied, you can appeal the decision.
Talk to your prescriber about a different form of progesterone that’s less costly or more likely to be covered by your insurance.
Look into other savings options, such as GoodRx discounts or patient assistance programs.
Ways to save on progesterone
There are ways to save on progesterone. The best option may depend on which form you’re prescribed.
1. Use a GoodRx coupon
A free GoodRx discount may help lower the cost of progesterone. The table below compares the lowest GoodRx price at certain pharmacies with the average cash price for common forms and doses of progesterone.
Dose, form, and quantity | Average cash price | GoodRx low price |
|---|---|---|
Progesterone 100 mg, 30 capsules | ||
Progesterone 200 mg, 30 capsules | ||
Progesterone in oil 50 mg/mL injection 10 mL, 3 vials | ||
Progesterone 100 mg, 21 vaginal inserts (generic Endometrin) | ||
Crinone 8% vaginal gel, 15 applicators |
To save with a GoodRx coupon:
Visit www.goodrx.com or download the app.
Search for “progesterone” or “Crinone,” and then click or tap “Find the lowest prices.”
Select your prescribed dosage form, dose, and quantity.
Choose if you want to receive the discount information by text or email. You can also take a screenshot on your phone or save it to your phone’s digital wallet.
To avoid delays, give the discount information to the pharmacy before you pick up your prescription.
Keep in mind: GoodRx savings may vary by pharmacy and geographic location. The GoodRx website and app can help you compare prices in your area.
2. Enroll in GoodRx Companion
You can access discounted prescription medications with a GoodRx Companion subscription. Over 250 medications are available for free, with hundreds more under $10 per month.
The GoodRx Companion program also includes benefits to help you cut your self-pay costs, such as lower prices for online care visits, discounts on dental care, and other health service savings.
3. See if you qualify for a copay savings card
You can pay as little as $15 per prescription of Crinone 8% with a copay savings card from the manufacturer. There is a maximum benefit of $200 per month ($2,400 per year) for this program. To be eligible, you must:
Have commercial insurance coverage for Crinone 8%
Not have government-funded insurance, such as Medicare or Medicaid
Reside in the U.S., including Puerto Rico
4. Check if you’re eligible for a patient assistance program
If you’re taking progesterone as part of a fertility treatment plan, there are several assistance programs available that can help cover some of your costs, such as The Hopeful Mama Foundation. Resolve: The National Infertility and Family Building Association, also offers a comprehensive list of grants and scholarships you can apply for.
If you are uninsured or underinsured and meet income criteria, you may be able to receive Crinone free of cost through AbbVie’s patient assistance program. You can access the application online or call 1-800-222-6885 for more information.
5. Tap into your HSA, FSA, or HRA
If you have a health savings account (HSA), flexible spending account (FSA), or health reimbursement arrangement (HRA), you can use it to help cover your out-of-pocket costs for phentermine. These tax-advantaged healthcare accounts let you pay for eligible expenses with tax-free dollars.
Pay directly with your HSA or FSA card at the pharmacy, or cover the cost yourself and request reimbursement. The funds in HSAs and some HRAs roll over annually. But you have to use FSA dollars before the plan’s deadline or they’ll expire.
The bottom line
Progesterone comes in several prescription forms, including capsules (Prometrium), an injection, and vaginal inserts (Endometrin) or gel (Crinone). All forms of progesterone, except Crinone, are available as lower-cost generics.
How much progesterone costs depends on which form you’re using and whether or not you have insurance, among other factors. Without insurance, the average cash price of 30 progesterone 100 mg capsules is $49.14. But you could pay as little as $15.00 for the same prescription with a free GoodRx discount. A manufacturer savings card and patient assistance program are also available for brand-name Crinone.
Why trust our experts?
References
AbbVie. (2024). Application for patient access support.
AbbVie. (n.d.). Available programs.
Crinone progesterone gel. (n.d.). Crinone 8% savings program. AbbVie.
Hopeful Mama Foundation. (n.d.). Supporting women on their journey as a hopeful mama.
Resolve: The National Infertility and Family Building Association. (2025). Fertility treatment scholarships and grants.
