The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Fatigue (57%)
- Low blood cell counts (up to 54%)
- Diarrhea (32%)
- Bloody nose (31%)
- Swelling in the arms and legs (25%)
- High blood pressure (25%)
- Mouth sores (20%)
Less Common Side Effects
- Bleeding in the stomach
Please note: These side effects were reported by people who took [[EDITOR|DRUG_DISPLAY_NAME]] with paclitaxel (Taxol) for stomach cancer in a clinical study.
Cyramza serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Severe bleeding: lightheadedness, black or bloody stools, coughing up blood or vomit that looks like coffee grounds
- Stomach or intestinal injury: severe vomiting, diarrhea, abdominal pain that doesn't go away
- Blood clots in the arteries: chest pain, sudden severe headaches, trouble breathing, sudden changes in speech or vision
- High blood pressure: severe headache, lightheadedness, confusion
- Posterior reversible encephalopathy syndrome: headache, feeling sluggish or confused, blindness
- Infusion-related reactions: chest pain, tremors, back pain, chills, trouble breathing, feeling flushed
Source: DailyMed
The following Cyramza side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Bleeding—bloody or black, tar-like stools, vomiting blood or brown material that looks like coffee grounds, red or dark brown urine, small red or purple spots on skin, unusual bruising or bleeding
- Dizziness, loss of balance or coordination, confusion or trouble speaking
- Heart attack—pain or tightness in the chest, shoulders, arms, or jaw, nausea, shortness of breath, cold or clammy skin, feeling faint or lightheaded
- Increase in blood pressure
- Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
- Infusion reactions—chest pain, shortness of breath or trouble breathing, feeling faint or lightheaded
- Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Low thyroid levels (hypothyroidism)—unusual weakness or fatigue, increased sensitivity to cold, constipation, hair loss, dry skin, weight gain, feelings of depression
- Stomach pain that is severe, does not go away, or gets worse
- Stroke—sudden numbness or weakness of the face, arm, or leg, trouble speaking, confusion, trouble walking, loss of balance or coordination, dizziness, severe headache, change in vision
- Sudden and severe headache, confusion, change in vision, seizures, which may be signs of posterior reversible encephalopathy syndrome (PRES)
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
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