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Avastin

Avastin Side Effects

Sonja Jacobsen, PharmD, BCPS, BCOPConnie Zheng, PharmD
Reviewed by Sonja Jacobsen, PharmD, BCPS, BCOP, Connie Zheng, PharmD
Last reviewed on March 29, 2023

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

The side effects below were reported by more than 10% of the people who received [[EDITOR|DRUG_DISPLAY_NAME]] in clinical trials:

  • Nose bleeds
  • Headache
  • High blood pressure
  • Runny nose
  • Higher levels of protein in urine test
  • Changes in taste
  • Dry skin
  • Bleeding that’s difficult to stop
  • Dry eyes or too much tears
  • Back pain
  • Peeling or blistering skin

Please note: You might receive [[EDITOR|DRUG_DISPLAY_NAME]] along with other medications. If so, ask your provider what side effects you might expect from other anticancer medications you're taking.

Avastin serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Tears in the gut: fever, chills, intense stomach pain or cramps, bloating
  • Fistulas: skin irritation around the anus, discharge from the anus, swelling or redness around the anus, blood in the stool
  • Serious bleeding (general): unusual bleeding, bleeding that’s difficult to stop, easy bruising, blood in urine or stool
  • Bleeding in the lungs: Chest pain, cough, trouble breathing, wheezing, fast heartbeat
  • Stomach bleeds: tiredness, vomiting blood, stomach cramps, black or tarry stool, blood in the stool
  • Stroke: sudden numbness or weakness in the arm, leg, or face, confusion, trouble seeing, headache, difficulty walking
  • Blood clot in the lungs: cough, chest pain, trouble breathing, racing heart
  • Blood clot in the heart: chest pain, stomach discomfort, sweating, nausea, dizziness
  • Blood clot in the leg: leg cramp, swelling, pain, muscle tightness
  • Dangerously high blood pressure: anxiety, blurry vision, confusion, chest pain, nausea, vomiting, headache
  • Dangerously high blood pressure: anxiety, blurry vision, confusion, chest pain, nausea, vomiting, headache
  • Serious kidney problems: trouble thinking clearly, nausea, vomiting, feeling very tired, urinating less than usual, cloudy-looking urine
  • Serious infusion reactions: trouble breathing, itching or hives, flushing, swelling, chest pain, fast heartbeat, dizziness, fainting

Source: DailyMed

The following Avastin side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Black, tarry stools

bleeding gums

body aches or pain

burning, tingling, numbness, or pain in the hands, arms, feet, or legs

chest pain, discomfort, or tightness

chills

cloudy urine

cough

cracks in the skin

decreased urine output

difficult or labored breathing

dilated neck veins

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

ear congestion

fever

irregular breathing

irregular heartbeat

lack or loss of strength

lightheadedness

loss of appetite

loss of heat from the body

loss of voice

mood changes

nervousness

pain

pain, redness, or swelling in the arm or leg

painful or difficult urination

pinpoint red spots on the skin

pounding in the ears

rapid breathing

redness of the skin

runny or stuffy nose

seizures

sensation of pins and needles

slow or fast heartbeat

sore throat

sores on the skin

sores, ulcers, or white spots on the lips or in the mouth

stabbing pain

sunken eyes

sweating

swelling of the face, fingers, feet, or lower legs

swelling or inflammation of the mouth

swollen glands

thirst

trouble breathing

unusual bleeding or bruising

unusual tiredness or weakness

vomiting of blood or material that looks like coffee grounds

watery or bloody diarrhea

weight gain

wrinkled skin

yellow skin

Less common

Bone pain

difficulty with swallowing

fainting

severe constipation

severe vomiting

stomach pain or tenderness

Rare

Back pain

blisters

blurred vision

confusion

dizziness

drowsiness

headache

increased thirst

loss of consciousness

muscle pain or cramps

open sores

pale skin

Incidence not known

Bloody mucus or unexplained nosebleeds

constipation

diarrhea

heartburn

heavy jaw feeling

high fever

hoarseness

indigestion

loosening of a tooth

nausea

pain, swelling, or numbness in the mouth or jaw

stomach cramping or burning

stomach pain, usually after eating a meal

sudden weakness in the arms or legs

sudden, severe chest pain

unexplained bleeding or bruising

unusual tiredness or weakness

voice changes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Belching

bloody nose

change in taste or bad unusual or unpleasant (after) taste

change in walking and balance

clumsiness or unsteadiness

dry mouth

excess flow of tears

hair loss

stomach discomfort or upset

thinning of the hair

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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