Key takeaways:
Most people with COVID don’t need to go to the hospital. Mild and moderate infections can often be treated at home.
Severe COVID symptoms that need medical attention include difficulty breathing, confusion or disorientation, and a bluish discoloration in the lips or hands.
In the emergency room, healthcare professionals can check your vital signs and run some tests to see if it’s safe for you to go home or if you need to stay in the hospital.
Most people with COVID-19 infection never have to see a healthcare professional throughout the course of their illness. But in a world of self-testing and telehealth appointments, it’s totally normal to wonder if you’re OK at home. And it can be scary to know that COVID can still lead to severe health problems. We’re here to help you know when it’s time to get help.
What are the symptoms of severe COVID-19?
A COVID infection can make you feel very sick, even when you’re OK and not in any real danger. But it can be hard to know when it’s time to get medical attention.
It’s important to remember that COVID can cause severe symptoms, like difficulty breathing. It can also cause oxygen levels in your body to be dangerously low. If this happens, you need medical attention and supplemental oxygen right away.
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Your oxygen level might be low if you:
Feel like you’re working very hard to breathe
Feel like you can’t catch your breath
Experience chest pain or tightness
Notice a bluish or dusky discoloration of your skin, lips, or nail beds
Seem confused or disoriented
Have difficulty staying awake
If you’re used to feeling short of breath from an underlying condition, like asthma or chronic obstructive pulmonary disease (COPD), it's important to be extra cautious if you get a COVID infection. Pay attention to any symptoms that seem different or worse than your baseline.
What are the risk factors for severe COVID?
Certain conditions put you at greater risk for developing severe COVID infections compared to the average population. Some of the more common risk factors include:
Age over 50 years old
Higher body weight or body fat
Chronic lung disease
HIV (human immunodeficiency virus)
You’re also at greater risk for severe COVID if you have:
Received an organ transplant
Had an illness that required steroids or immunosuppressive medications
Not been vaccinated against COVID
How do you get over COVID faster? There are some treatments and things you can do at home to help you get on the road to recovery sooner.
Finding Paxlovid and Lagevrio: These prescription medications can shorten the duration and severity of COVID. Here’s how to get them.
How long are you contagious with COVID? We walk you through the typical timeline of the infection — including when you are most contagious.
What to do if you have a higher risk of severe COVID
If any of the above risk factors apply to you, there are a few extra things you can do to look out for signs or symptoms of a more severe disease:
Stay in tune with your body. Take note of how you feel day to day so you can sense if your symptoms are worsening.
When in doubt, see a healthcare professional. Don’t wait until you feel really sick. If you’re unsure if you’re OK, reach out to your primary care provider to discuss your symptoms. They can also help you decide if you need to be seen right away in an ER.
Consider getting a pulse oximeter. This little device, which you put on your finger, measures your oxygen levels. In normal conditions, most people have a reading over 95%. If that reading consistently drops below this, it’s time to go to the ER.
What happens if you go to the ER for COVID-19?
When you go to the ER for COVID, one of the most important parts of your evaluation will be checking your vital signs. These include your:
Oxygen level (sometimes called “pulse ox”)
Breathing rate
Heart rate
Blood pressure
Depending on your vital signs and physical exam, your care team may also run some additional tests to see how the virus is affecting your body. These tests may include:
X-ray of your lungs to look for signs of pneumonia or fluid
CT scan of your chest to look at the lungs in greater detail or to check for blood clots
Electrocardiogram (ECG) of your heart to look for signs of stress or strain on your heart
Blood tests to check your blood counts, kidney function, and electrolytes
After these tests, you’ll discuss if you’re safe to continue recovering at home or if you should stay in the hospital for closer monitoring.
What happens when you are admitted to the hospital?
Your care team in the ER will probably recommend you stay in the hospital if:
You’re struggling to breathe.
Your oxygen levels are low.
You’re struggling to stay hydrated or keep fluids down.
You have any changes in how alert or sleepy you are, or how coherent you seem.
You have a medical condition that makes it more likely that your infection will worsen.
In the hospital, a healthcare professional can monitor you and your symptoms more closely.
Treatments for COVID
In addition to close monitoring, you can get helpful COVID treatments in the hospital. Every person is different and has different needs. But some treatment options include:
Oxygen, given through nasal prongs or a mask
Intravenous (IV) fluids to keep you well hydrated
Steroids, if you have underlying lung conditions
Antiviral medications, like remdesivir
Biologic medications, like vilobelimab or tocilizumab
Anti-inflammatory medications, like baricitinib or anakinra
Blood-thinning medications, like aspirin or enoxaparin (Lovenox), to reduce the chance of blood clots
Keep in mind that getting admitted to the hospital doesn’t mean that you’ll definitely have COVID-related complications. Hospitalization is often done to prevent that from happening. And if issues come up, your care team can treat them right away.
The bottom line
If you get a COVID-19 infection, it can be scary to think of the potential complications. The good news is that most people have mild to moderate disease and make a full recovery at home. It’s still important to know the signs and symptoms of a more severe infection — especially so you know when you or a loved one should get checked out in the ER. When in doubt, get medical attention for your symptoms.
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References
Centers for Disease Control and Prevention. (2024). Respiratory viruses and people with weakened immune systems.
Centers for Disease Control and Prevention. (2025). Underlying conditions and the higher risk for severe COVID-19.








