Ankylosing spondylitis (AS) is a chronic autoimmune disease that causes chronic back pain and stiffness. There is currently no “cure,” but treatment options can help manage the condition. Because of this, it may be hard to know if your AS medication is effective. One way to do this is by knowing your AS treatment goals.
“It is important to establish treatment goals with your physician [to help you] get back to your functional status,” says Maggie Cadet, MD, Rheumatologist in New York City.
Treatment goals may vary slightly for each person. Common treatment goals for ankylosing spondylitis generally include:
Reducing pain, stiffness, and other AS symptoms
Improving mobility and preserving range of motion
Preventing spinal fusion
Preventing other related complications throughout the body, such as psoriasis or eye disease
Maintaining good posture
A treatment plan for AS often includes some combination of:
Medications
Posture training
Physical therapy
Surgery
Not every person with AS will need all of these elements in their treatment plan. For example, not everyone will need surgery. Early and effective treatment for AS may help delay or prevent the need for surgery.
If you are not meeting your treatment goals, your care team may suggest changing parts of your treatment regimen. This may include changing your medication dose or switching to a different medication.
There are many medications available for ankylosing spondylitis that work in different ways. As a result, many people with AS are able to find a medication that works for them and helps them meet their goals.
The most common medication options for AS include:
NSAIDs (nonsteroidal anti-inflammatory drugs) to reduce symptoms of mild-to-moderate AS
Corticosteroid injections to relieve short-term flares to specific areas
DMARDs (disease-modifying antirheumatic drugs) to relieve symptoms and reduce joint damage, possibly changing the trajectory of your disease
Biologics to target specific parts of the immune system that fuel AS activity, also aiming to reduce the long-term severity of the disease
It may feel discouraging if you’re not getting ideal results from a medication. This feeling is valid, but there’s also good reason to stay optimistic.
“There are many options out there, and if you’re not feeling that something’s working for you, it is important to speak up,” says Dr. Cadet. “You know your body best, and it’s important to advocate for yourself to find the treatment option that works for you.
American College of Rheumatology. (2021). Spondyloarthritis.
National Institute of Arthritis and Musculoskeletal and Skin Diseases. (2020). Ankylosing spondylitis.
National Institute of Arthritis and Musculoskeletal and Skin Diseases. (2020). Ankylosing spondylitis: diagnosis, treatment, and steps to take.
Wenker, K. J., et al. (2022). Ankylosing spondylitis. StatPearls [Internet].