Key takeaways
Voltaren gel (diclofenac) and Celebrex (celecoxib) are both NSAIDs used to relieve pain, but they have some key differences. Voltaren gel is a topical medication applied directly to the skin, primarily used for osteoarthritis pain in smaller joints like the hands and knees. In contrast, Celebrex is an oral medication used for a broader range of conditions, including osteoarthritis, rheumatoid arthritis, and menstrual cramps. Voltaren gel can be purchased over-the-counter in its 1% form, while Celebrex requires a prescription. Celebrex is a COX-2 selective NSAID, which means it generally has a lower risk of causing stomach issues compared to other oral NSAIDs. However, both medications carry risks of serious side effects like heart attack and stroke. Voltaren gel is less likely to cause systemic side effects compared to oral NSAIDs, but it can cause skin irritation.
