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Victoza vs. Trulicity

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Victoza (liraglutide) and Trulicity (dulaglutide) are both injectable medications used to manage Type 2 diabetes, but they have some key differences. Victoza is injected once daily, while Trulicity is injected once a week, which might be more convenient for some people. Both medications are GLP-1 agonists that help lower blood sugar by increasing insulin release, reducing sugar production, and slowing digestion. They also lower the risk of major heart events in adults with Type 2 diabetes and heart disease. Common side effects for both include nausea, vomiting, and diarrhea. They both carry an increased risk of thyroid cancer, so they’re not recommended for people with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

Victoza

(liraglutide)

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Trulicity

(dulaglutide)

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Summary for Victoza

Prescription only

Victoza (liraglutide) is a medication that's injected once a day. It helps lower blood sugar levels in people 10 years and older with Type 2 diabetes when used with a nutritious diet and regular exercise. It can also help lower the risk of heart-related problems in adults with Type 2 diabetes and heart disease. Victoza (liraglutide) belongs to the drug class called GLP-1 agonists. The medication comes as single-dose prefilled pens and is injected under the skin. It can cause side effects like nausea, vomiting, diarrhea, and constipation. Victoza (liraglutide) is available as both a brand-name and generic medication.

Indications for Victoza

  • Type 2 diabetes in people age 10 and older, together with a balanced diet and exercise
  • Lowering the risk of serious heart-related problems in adults with Type 2 diabetes and heart disease

Pros and Cons for Victoza

Pros

  • Lowers A1C by up to 1% over a year
  • Can take with or without food at any time of day
  • Available as an injectable pen

Cons

Common Side Effects for Victoza

Warnings for Victoza

  • Possible risk of thyroid cancer
  • Inflammation of the pancreas (pancreatitis)
  • Low blood sugar (hypoglycemia)
  • Kidney damage
  • Allergic reactions
  • Gallbladder problems
  • Lung problems during general anesthesia or deep sedation

Summary for Trulicity

Prescription only

Trulicity (dulaglutide) is a glucagon-like peptide-1 (GLP-1) agonist that helps control blood sugar in people 10 years and older with Type 2 diabetes. It's also approved to lower the risk of heart problems like heart attacks, strokes, and heart-related death in certain adults with Type 2 diabetes. The medication is injected under the skin once a week. Common side effects include nausea, vomiting, diarrhea, and stomach pain. When taken with certain diabetes medications like insulin, there's a higher risk of low blood sugar (hypoglycemia).

Indications for Trulicity

  • Manage Type 2 diabetes in people 10 years and older, along with diet and exercise
  • Lower the risk of heart problems like heart attack, stroke, or death in adults with Type 2 diabetes who have heart disease or heart-related risk factors

Pros and Cons for Trulicity

Pros

  • Works well at lowering A1C
  • Comes as a ready-to-use injectable pen
  • Only used once a week
  • Helps with weight loss

Cons

  • Commonly causes nausea, vomiting, diarrhea, and stomach pain
  • Potential risk for thyroid tumors
  • Can cause problems in the pancreas, kidney, and gallbladder
  • Not recommended for people with stomach problems

Common Side Effects for Trulicity

  • Nausea (12-21%)
  • Diarrhea (7-13%)
  • Vomiting (6-13%)
  • Stomach pain (7-9%)
  • Low appetite (5-9%)
  • Fatigue (4-6%)
  • Indigestion (3-6%)

Warnings for Trulicity

  • Thyroid cancer
  • Inflammation of the pancreas (pancreatitis)
  • Low blood sugar when used with certain diabetes medications
  • Severe allergic reactions
  • Kidney damage
  • Severe stomach-related side effects
  • Worsening eye problems in people with diabetic retinopathy
  • Gallbladder problems
  • Breathing fluid into your lungs during anesthesia or deep sedation

Prices with our coupons for Victoza vs. Trulicity

Price Card Drug Icon
Liraglutide (Victoza)1 carton / 3 pens of 18mg/3ml
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Trulicity1 carton / 4 pens of 0.75mg/0.5ml
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