Key takeaways
Retin-A (tretinoin) and Botox (onabotulinumtoxinA) are both prescription medications used for skin-related conditions, but they belong to different medication classes and have distinct uses. Retin-A is a retinoid used topically to treat acne, while Botox is a neuromuscular blocker injected to address various conditions, including muscle spasms and excessive sweating. Both medications are also often used to reduce wrinkles. Retin-A is applied as a cream or gel once daily, typically at bedtime. Botox is injected by a healthcare professional, and is only available as a brand-name medication. Common side effects of Retin-A include skin irritation and increased sensitivity to sunlight, whereas Botox can cause urinary tract infections, neck pain, and muscle weakness, among other side effects.
