Key takeaways
Retin-A (tretinoin) and BenzeFoam (benzoyl peroxide) are both prescription acne medications, but they contain different active ingredients and work in different ways. Retin-A contains tretinoin, a topical retinoid that increases skin cell turnover to help unclog pores and prevent new acne from forming. BenzeFoam contains benzoyl peroxide, which kills acne-causing bacteria, reduces inflammation, and helps clear excess oil from the skin. Retin-A is typically used once daily in the evening, while BenzeFoam is usually applied once or twice daily. Both medications can cause skin irritation, dryness, and peeling, especially when treatment begins. BenzeFoam may also bleach hair, clothing, and towels. In some cases, your presriber may recommend both medications together since they work differently to control acne.
