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Tenex vs. Xanax

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Guanfacine and alprazolam (Xanax) are both prescription medications, but they have some key differences. Guanfacine is an alpha-2 adrenergic receptor agonist used to treat high blood pressure and is typically taken once a day at bedtime. In contrast, alprazolam is a benzodiazepine used to treat generalized anxiety disorder (GAD) and panic attacks, and it is usually taken three times a day. Guanfacine is not a controlled substance, while alprazolam is a Schedule IV controlled medication due to its potential for dependence and misuse. Common side effects of guanfacine include sleepiness, dizziness, and dry mouth, whereas alprazolam can cause drowsiness, memory problems, and lightheadedness. Additionally, alprazolam has a risk of addiction and withdrawal symptoms, making it suitable only for short-term use. Guanfacine does not have these risks but can cause anxiety and nervousness if stopped suddenly.

Guanfacine

 

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Alprazolam

(Xanax)

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Summary for Tenex

Prescription only

Guanfacine is used to treat high blood pressure, but it's not a first-choice option. It's taken by mouth, typically once a day at nighttime. Common side effects of guanfacine include sleepiness, dizziness, and dry mouth. Some medications, such as sleep medications or certain pain medications, can interact with guanfacine by worsening those side effects. The brand name Tenex is no longer available.

Indications for Tenex

Pros and Cons for Tenex

Pros

  • Available in a lower-cost generic version
  • Taken once a day
  • Taken by mouth

Cons

  • Not a first-choice option for treating high blood pressure
  • Stopping suddenly can lead to anxiety and nervousness
  • Can cause sleepiness and dizziness

Common Side Effects for Tenex

  • Dry mouth (up to 54%)
  • Sleepiness (up to 39%)
  • Dizziness (up to 15%)
  • Constipation (up to 15%)
  • Headache (up to 13%)
  • Weakness (up to 10%)
  • Tiredness (up to 10%)

Warnings for Tenex

  • Extreme sleepiness and dizziness
  • Nervousness and anxiety (from stopping guanfacine too suddenly)

Summary for Xanax

Prescription only

Alprazolam (Xanax) is a benzodiazepine. It's approved to treat generalized anxiety disorder (GAD) and panic attacks in adults. It's taken by mouth, typically 3 times a day or as directed by your healthcare team. To avoid the risk of dependence, alprazolam (Xanax) is meant for short-term treatment only. Some of the more common side effects of this medication include drowsiness and memory problems. You should avoid drinking alcohol while taking alprazolam (Xanax) because this can lead to serious interactions.

Indications for Xanax

Pros and Cons for Xanax

Pros

  • Taken by mouth
  • Can start to work in 30 minutes
  • Available as quick-dissolving tablets or liquid for people who have trouble swallowing pills

Cons

Common Side Effects for Xanax

Generalized anxiety disorder:

  • Drowsiness (41%)
  • Lightheadedness (21%)
  • Dry mouth (15%)

Panic disorder:

  • Drowsiness (77%)
  • Fatigue (49%)
  • Poor coordination (40%)
  • Memory issues (33%)
  • Irritability (33%)
  • Appetite changes (28-33%)
  • Thinking problems (29%)
  • Constipation (26%)

Side effects listed are for the immediate-release forms. Side effects for extended-release form might differ.

Warnings for Xanax

  • Sedation and difficulty breathing
  • Potential for misuse, addiction, dependence, and withdrawal
  • Effect on driving and concentration
  • Harm to babies
  • Interactions with other medications
  • Use with caution in people with depression

Prices with our coupons for Tenex vs. Xanax

Price Card Drug Icon
Guanfacine30 tablets / 1mg
$13.64$33.58
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Alprazolam30 tablets / 0.5mg
$10.40$15.97
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