Head-to-head comparisons of medication uses, side effects, warnings, and more.
Key takeaways
Guanfacine and alprazolam (Xanax) are both prescription medications, but they have some key differences. Guanfacine is an alpha-2 adrenergic receptor agonist used to treat high blood pressure and is typically taken once a day at bedtime. In contrast, alprazolam is a benzodiazepine used to treat generalized anxiety disorder (GAD) and panic attacks, and it is usually taken three times a day. Guanfacine is not a controlled substance, while alprazolam is a Schedule IV controlled medication due to its potential for dependence and misuse. Common side effects of guanfacine include sleepiness, dizziness, and dry mouth, whereas alprazolam can cause drowsiness, memory problems, and lightheadedness. Additionally, alprazolam has a risk of addiction and withdrawal symptoms, making it suitable only for short-term use. Guanfacine does not have these risks but can cause anxiety and nervousness if stopped suddenly.
Guanfacine
Alprazolam (Xanax)
Guanfacine
Alprazolam (Xanax)
Summary of Tenex vs. Xanax
Summary for Alpha-2 adrenergic receptor agonist
Prescription only
Guanfacine is used to treat high blood pressure, but it's not a first-choice option. It's taken by mouth, typically once a day at nighttime. Common side effects of guanfacine include sleepiness, dizziness, and dry mouth. Some medications, such as sleep medications or certain pain medications, can interact with guanfacine by worsening those side effects. The brand name Tenex is no longer available.