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Propecia vs. Spironolactone

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Propecia (finasteride) and Aldactone (spironolactone) are both prescription medications, but they serve different purposes and belong to different drug classes. Propecia is a 5-alpha reductase inhibitor used to treat male pattern baldness by blocking the enzyme that converts testosterone to dihydrotestosterone (DHT), which can cause hair loss when levels are high. It is taken once daily and can cause sexual side effects like low sex drive and erectile dysfunction. On the other hand, Aldactone is a potassium-sparing diuretic used to treat conditions like heart failure, high blood pressure, and swelling due to kidney or liver problems. It works by blocking aldosterone, a hormone that affects sodium and potassium levels, and can cause side effects such as breast tenderness and lower sex drive in males. While both medications are available in generic forms, spironolactone also comes in an oral suspension for those who have difficulty swallowing tablets. Additionally, spironolactone requires regular blood tests to monitor electrolytes and kidney health, whereas finasteride does not.

Finasteride

(Propecia)

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Spironolactone

(Aldactone)

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Summary for Propecia

Prescription only

Finasteride (brand name Propecia) is a prescription medication used to treat male pattern baldness in adult men. It works by lowering levels of a hormone in your body that's linked to hair loss. You take it by mouth once a day, with or without food. Common side effects can include sexual problems, such as a lower sex drive, trouble getting or keeping an erection, or less semen during ejaculation.

Note: Finasteride (Propecia) is different from finasteride (Proscar) used to treat enlarged prostate.

Indications for Propecia

Pros and Cons for Propecia

Pros

  • FDA approved specifically for male pattern hair loss
  • Taken by mouth once per day
  • Can slow hair loss and support regrowth

Cons

  • Takes 3 months or longer to see the full benefits
  • Hair loss typically returns if stopped
  • Might cause sexual side effects

Common Side Effects for Propecia

  • Lower sex drive (2%)
  • Erectile dysfunction (1%)
  • Ejaculation problems (1%)

Warnings for Propecia

  • Harm to unborn baby boy
  • Changes to prostate-specific antigen (PSA) levels
  • Risk of prostate cancer

Summary for Spironolactone

Prescription only

Spironolactone (Aldactone) is a type of potassium-sparing diuretic (water pill). It's used to treat heart failure, high blood pressure, and swelling from kidney or liver problems in adults. Because it blocks aldosterone (a hormone that affects sodium and potassium levels), spironolactone (Aldactone) can also treat conditions where there's too much aldosterone. Spironolactone (Aldactone) is taken by mouth, generally once or a few times a day, depending on your condition. Some common side effects of this medication include breast tenderness (males and females) and loss of libido (in males).

Indications for Spironolactone

Pros and Cons for Spironolactone

Pros

  • Taken by mouth
  • Oral suspension available for adults who've difficulty swallowing tablets
  • Lower-cost generics available

Cons

  • Can make you urinate more often
  • Need to get blood tests regularly to check your electrolytes and kidney health
  • Can cause breast growth and lower sex drive in males

Common Side Effects for Spironolactone

  • Dizziness
  • Headache
  • Sleepiness
  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach cramps
  • Enlargement of male breasts
  • Breast pain
  • Lower sex drive
  • Sexual dysfunction
  • Irregular or lack of menstrual periods
  • Leg cramps
  • Higher potassium levels
  • Lower sodium levels

Warnings for Spironolactone

  • High blood potassium levels
  • Low blood pressure and kidney problems
  • Abnormal electrolyte levels
  • Breast pain or swelling

Prices with our coupons for Propecia vs. Spironolactone

Price Card Drug Icon
Finasteride30 tablets / 1mg
$10.20$12.88
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Spironolactone30 tablets / 25mg
$9.73-
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