Key takeaways
NuvaRing (etonogestrel / ethinyl estradiol) and Nexplanon (etonogestrel) are both medications used to prevent pregnancy, but they belong to different drug classes. NuvaRing is a combined contraceptive containing both progestin and estrogen, while Nexplanon is a progestin-only contraceptive. NuvaRing is a flexible plastic ring inserted into the vagina for three weeks, followed by a one-week break, and is available in both brand-name and generic forms. Nexplanon is a small implant placed under the skin of your upper arm by a healthcare professional and can prevent pregnancy for up to five years. Common side effects of NuvaRing include headaches and vaginal irritation, while Nexplanon may cause headaches and irregular bleeding. NuvaRing users need to be cautious about blood clots, especially if over 35 and smoking, whereas Nexplanon has a lower risk of blood clots due to the absence of estrogen. Both medications require a prescription, but Nexplanon involves a medical procedure for insertion and removal, while NuvaRing can be managed at home.
