Key takeaways
NuvaRing (etonogestrel / ethinyl estradiol) and Xulane (norelgestromin / ethinyl estradiol) are both medications used to prevent pregnancy and belong to the class of combined hormonal contraceptives. They both contain estrogen and progestin, which work by stopping ovulation, thickening cervical mucus, and altering the uterine lining. However, they differ in their form and application. NuvaRing is a flexible vaginal ring that you insert for three weeks, while Xulane is a transdermal patch that you apply to your skin once a week for three weeks. Both are available in both brand-name and generic versions. Common side effects of NuvaRing include vaginal irritation and headaches, while Xulane may cause breast discomfort and skin irritation. Both medications carry risks of serious side effects like blood clots, especially if you smoke and are over 35. Additionally, Xulane may not be as effective for individuals with a BMI of 30 kg/m² or higher. Always consult with your healthcare team to determine which option is best for you.
