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ETONOGESTREL is a contraceptive (birth control) device. It is used to prevent pregnancy. It can be used for up to 3 years. Compare progestins.
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What is Nexplanon?

Commonly Used Brand Name(s)Implanon, Nexplanon

Therapeutic ClassificationsContraceptive, Progestin

Pharmacologic ClassificationsProgestin

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OverviewTOP

Etonogestrel implant is a medicine that is used in women to prevent pregnancy. It is a form of birth control. This medicine contains a hormone in a flexible plastic rod about the size of a matchstick. It is effective for three years when inserted just beneath the skin of your upper arm.

Etonogestrel implant will not protect a woman from sexually transmitted diseases (STDs), including human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS). The use of latex (rubber) condoms or abstinence (not having sex) is recommended for protection from these diseases.

This medicine is available only with your doctor's prescription.

Proper UseTOP

It is very important that you tell your doctor if you think you might be pregnant or if you missed a period before you receive this medicine. Tests will be done to make sure you are not pregnant before this medicine is inserted.

This medicine comes with patient instructions. After reading the instructions, you will be asked to sign a USER CARD and a Patient Consent Form before you receive this medicine. The Consent Form tells you about some possible risks when using this medicine, and when it must be removed. Make sure you understand what is in the patient instructions and the Consent Form before you sign it. Keep the USER CARD in a safe place at home with your health records. If you have any questions, ask your doctor to answer them.

After this medicine is inserted, you should check that it is in place. Gently press your fingertips over the skin in your arm where this medicine was inserted. You should be able to feel the small rod.

You may have to use another form of birth control (e.g., condoms, diaphragms, or spermicides) until the implant has been in place for 7 days. Talk with your doctor about this.

Your doctor must remove this medicine after 3 years. If you would like to stop using this medicine, your doctor can remove it at any time.

If you still want to prevent pregnancy after this medicine is removed, you should start using another form of birth control (e.g., condoms, diaphragms, or spermicides) right away. If you still want to continue using this medicine, your doctor can insert a new implant under your skin after taking the old one out.

Before UsingTOP

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

AllergiesTOP

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

PediatricTOP

Appropriate studies on the relationship of age to the effects of etonogestrel implant have not been performed in the pediatric population. However, pediatric-specific problems that would limit the usefulness of this medication in teenagers are not expected. This medicine may be used for birth control in teenage females but should not be used before the start of menstruation.

GeriatricTOP

Appropriate studies on the relationship of age to the effects of etonogestrel implant have not been performed in the geriatric population. This medicine should not be used in elderly women.

Breast FeedingTOP

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug InteractionsTOP

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Carbamazepine
  • Dabrafenib
  • Darunavir
  • Eliglustat
  • Isotretinoin
  • Lesinurad
  • Lixisenatide
  • Lumacaftor
  • Pitolisant
  • Sugammadex
  • Theophylline
  • Ulipristal

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Other InteractionsTOP

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Caffeine

Other Medical ProblemsTOP

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Abnormal or unusual vaginal bleeding (non-menstrual) or
  • Breast cancer, now or in the past or if suspected or
  • Cancer (progestin-sensitive), now or in the past or
  • Liver disease, active or
  • Liver tumors, benign or malignant—Should not be used in patients with these conditions.
  • Blood clots, now or in the past—Should not be used in patients with blood clots in the brain, legs, lungs, eyes, or heart.
  • Obesity—This condition may cause the medicine to not work as well.

PrecautionsTOP

If you will be using the etonogestrel implant for a long time, it is very important that your doctor check you at regular visits for any problems or unwanted effects that may be caused by this medicine.

If you become pregnant while using this medicine, you have a slightly higher chance of having an ectopic pregnancy (occurs outside the womb). Ectopic pregnancies can cause serious internal bleeding. Contact your doctor immediately to have the implant removed.

Tell your doctor if you are breastfeeding or planning to breastfeed. You may start using this medicine if you had a baby more than 4 weeks ago.

Etonogestrel implant will not protect you against HIV/AIDS or other sexually transmitted diseases. The use of latex (rubber) condoms or abstinence (not having sex) is recommended for protection from these diseases.

Tell your doctor if you have had an allergic reaction to numbing medicines (anesthetics) or skin cleansers (antiseptics). These medicines will be used when etonogestrel implant is inserted into your arm.

This medicine may cause several problems related to insertion and removal, such as pain, irritation, swelling, bruising, scarring, or other complications. Talk to your doctor about these possible risks.

Using this medicine may increase your risk of blood clots in the legs (deep vein thrombosis), lungs (pulmonary embolism), brain (stroke), heart (heart attack), or eyes (blindness). Make sure your doctor knows at least 4 weeks before if you are going to have a surgery or will need to be on bed rest. Your risk of these serious medical problems is greater during surgery or bed rest, or if you smoke cigarettes.

This medicine may also increase your risk of having irregular monthly periods, ovarian cysts, high blood pressure, gallbladder problems, or liver tumors.

Call your doctor right away if you have pain or tenderness in the upper stomach; pale stools; dark urine; loss of appetite; nausea; unusual tiredness or weakness; or yellow eyes or skin. These could be symptoms of a serious liver problem.

If you wear contact lenses and you have blurred vision, difficulty in reading, or any other change in vision while using this medicine, check with your doctor right away. Your doctor may want you to get your eyes checked by an eye doctor (ophthalmologist).

This medicine may affect blood sugar levels. If you notice a change in the results of your blood or urine sugar tests, or if you have any questions, check with your doctor.

Before you have any medical tests, tell the medical doctor in charge that you are using etonogestrel implant. The results of some tests may be affected by this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (St. John's wort) or vitamin supplements.

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