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Nexplanon Coupon - Nexplanon 68mg implant

Nexplanon

etonogestrel
Used for Birth Control
Used for Birth Control

Nexplanon (etonogestrel) is an implant placed in your arm to prevent pregnancy. It's a long-acting medication that continues to prevent pregnancy for up to 3 years after insertion. It's one of the most effective forms of birth control available. Unlike other birth control options that contain two hormones (estrogen and progesterone), Nexplanon (etonogestrel) only contains a progesterone called etonogestrel. The most common side effects include irregular vaginal bleeding (e.g., longer periods, spotting) and headaches.

Last reviewed on July 16, 2023
basics-icon

What is Nexplanon (etonogestrel)?

What is Nexplanon (etonogestrel) used for?

  • To prevent pregnancy

How Nexplanon (etonogestrel) works

The Nexplanon (etonogestrel) implant slowly releases etonogestrel, which is a progestin (a manmade form of progesterone). It works to prevent pregnancy by stopping your ovaries from releasing an egg, by making it difficult for sperm to enter the uterus (womb), and by preventing a fertilized egg from implanting in your uterus.

Drug Facts

Common BrandsNexplanon
Drug ClassProgestin
Controlled Substance ClassificationNot a controlled medication
Generic StatusNo lower-cost generic available
AvailabilityPrescription only

More on Nexplanon (etonogestrel) essentials

basics-icon

What are the side effects of Nexplanon (etonogestrel)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache (25%)
  • Absence of period (20%)
  • More frequent or longer vaginal bleeding (20%)
  • Vaginal pain or itching (15%)
  • Weight gain (14%)
  • Acne (14%)
  • Breast pain (13%)
  • Stomach pain (11%)
  • Sore throat (11%)
  • Vaginal discharge (10%)

Other Side Effects

  • Flu-like symptoms
  • Dizziness
  • Menstrual cramps
  • Back pain
  • Body pain
  • Pain at insertion site
  • Nausea
  • Mood swings
  • Nervousness
  • Depression

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Ectopic pregnancy: severe, unexplainable pelvic pain, unusual vaginal bleeding
  • Heart attack: chest pain or tightness, pain that radiates up to your shoulder, arm, neck, or jaw
  • Stroke: sudden trouble talking, trouble walking, numbness on one side of your body or face, sudden, severe headaches
  • Blood clot in the lungs: trouble breathing, chest pain
  • Breast lumps or pain

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Breast pain

chills

cough

diarrhea

fever

general feeling of discomfort or illness

headache

joint pain

loss of appetite

muscle aches and pain

nausea

runny nose

shivering

sore throat

sweating

trouble sleeping

unusual tiredness or weakness

vomiting

Less common

Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the insertion site

bloating

blurred vision or other changes in vision

breast discharge

breast enlargement

burning feeling while urinating

difficult or painful urination

difficulty with breathing

difficulty with swallowing

dizziness

headache, severe and throbbing

lumps in the breasts

nervousness

noisy breathing

painful or tender cysts in the breasts

pounding in the ears

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

shortness of breath

skin rash, hives, itching

slow or fast heartbeat

stomach or pelvic discomfort, aching, or heaviness

swelling of the hands, ankles, feet, or lower legs

tightness in the chest

Rare

Collection of blood under the skin at the insertion site

deep, dark purple bruise at the insertion site

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain

blemishes on the skin, pimples

body aches or pain

crying

depersonalization

discouragement

dysphoria

ear congestion

euphoria

feeling sad or empty

hoarseness

increased clear or white vaginal discharge

increased weight

irregular bleeding cycle

irritability

itching of the vagina or genital area

light vaginal bleeding between regular menstrual periods

loss of interest or pleasure

loss of voice

mental depression

nasal congestion

pain, cramps, or heavy menstrual bleeding

pain during sexual intercourse

pain or tenderness around the eyes and cheekbones

paranoia

quick to react or overreact emotionally

rapidly changing moods

stomach pain

tender, swollen glands in the neck

thick, white vaginal discharge with no odor or with a mild odor

trouble concentrating

voice changes

Less common

Abnormal ejaculation

abnormal or decreased touch sensation

belching

bone pain

burning feeling in the chest or stomach

decreased interest in sexual intercourse

difficulty having a bowel movement

difficulty with moving

dull ache or feeling of pressure or heaviness in the legs

excess air or gas in the stomach or intestines

feeling of vaginal pressure

feeling of warmth

hair loss or thinning of the hair

heartburn

inability to have or keep an erection

increased appetite

increased hair growth on the forehead, back, arms, and legs

indigestion

itching skin near damaged veins

lack or loss of strength

loss in sexual ability, desire, drive, or performance

muscle cramping or stiffness

passing gas

pelvic pain

redness of the face, neck, arms, and occasionally upper chest

redness, swelling in the ear, or earache

sleepiness or unusual drowsiness

sneezing

stomach bloating and cramping

stuffy nose

swollen joints

tenderness in the stomach area

vaginal burning or pain

weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Nexplanon (etonogestrel)

thumbs-up

Pros

Works better than oral birth control pills to prevent pregnancy

Can be inserted in your provider's office within a few minutes and without any kind of sedation (medication to put you asleep)

Continues working for 3 years and doesn't require you to remember to take the medication every day

Can be used while breastfeeding as long as it's been 4 weeks since you gave birth

A possible lower-cost birth control option for people without insurance

thumbs-down

Cons

Can raise your risk of an ectopic pregnancy if you do get pregnant

Breakthrough bleeding and irregular cycles are common side effects.

Can raise your blood pressure

Might lead to mood changes or depression

Risk of Nexplanon (etonogestrel) implant moving and not working well

pharmacist-tips

Pharmacist tips for Nexplanon (etonogestrel)

pharmacist
  • Nexplanon (etonogestrel) will be inserted by a healthcare provider in their office and keeps working for 3 years after it's placed. It can be removed before then if you want to try to get pregnant.

    • If you get Nexplanon (etonogestrel) removed, you should start another form of birth control right away if you don't wish to become pregnant. In medical studies, some people were able to get pregnant as early as 1-2 weeks after Nexplanon (etonogestrel) was removed.

      • After your provider places Nexplanon (etonogestrel), they'll cover it with two bandages. Don't remove the larger, top bandage for at least 24 hours. Keep the smaller, bottom bandage clean, dry, and in place for 3 to 5 days after.

        • Make sure you can always feel your implant. If there's ever a time you can't feel Nexplanon (etonogestrel), call your provider right away. This could be a sign that the implant has moved, meaning you could get pregnant. Use a barrier method of protection (e.g., condoms, diaphragms) to prevent pregnancy until your provider confirms the implant is in the right place.

          • When you go in for your yearly health checkup, ask your provider to feel whether Nexplanon (etonogestrel) is still in place.

            • If you experience an injury at or around the area of the Nexplanon (etonogestrel) implant, let your provider know right away. Though rare, injuries can cause the implant to break. This can affect how well Nexplanon (etonogestrel) works.

              • Nexplanon (etonogestrel) can be used while breastfeeding as long as it's been at least 4 weeks since you gave birth. The medication from the implant will not hurt your baby, but you might notice a slight drop in your milk supply.

                • Nexplanon (etonogestrel) doesn't protect you from HIV or other sexually transmitted infections (STIs). Only abstinence and condoms can help protect you from STIs. Talk to your provider right away if this is a concern for you.

                  • Nexplanon (etonogestrel) can affect your menstrual cycle and menstrual bleeding. It's possible you might even have no period while using the implant. Call your provider if this is concerning to you or if your bleeding becomes very heavy.

                    • Nexplanon (etonogestrel) can cause mood changes. If you've been depressed in the past or are currently experiencing depression, ask your family or loved ones to tell if they notice any changes in your mood. If Nexplanon (etonogestrel) is affecting your mood too much, you might want to talk with your provider about other options for birth control.

                      • There are several medications that can make birth controls, including Nexplanon (etonogestrel), not work as well. Discuss all medications you take with your provider before having the implant placed. Before starting any new medications, ask your pharmacist or provider if they'll interact with Nexplanon (etonogestrel).

                        More on Nexplanon (etonogestrel) tips

                        faqs

                        Frequently asked questions about Nexplanon (etonogestrel)

                        How long does Nexplanon (etonogestrel) last?
                        Nexplanon (etonogestrel) is long-acting and can prevent pregnancy for up to 3 years. If you choose to continue using Nexplanon (etonogestrel), you'll need to get it removed after 3 years and have a new one placed by your healthcare provider.
                        How long does it take for Nexplanon (etonogestrel) to work?
                        If Nexplanon (etonogestrel) is placed within 5 days of starting your period, it will work right away to prevent pregnancy. This means you won't need to use a back-up birth control method, such as condoms. If it's placed after the fifth day of your period starting, you'll need to use a back-up method for the first 7 days after insertion. If you're switching from another birth control method, talk to your provider about when you can expect Nexplanon (etonogestrel) to start working and if you need to use a back-up method at first.
                        How effective is Nexplanon (etonogestrel)?
                        Nexplanon (etonogestrel) is one of the most effective methods of birth control available. It is over 99% effective, meaning that fewer than one person out of every 100 gets pregnant while using this medication for 1 year. Pregnancy is more likely to happen if your implant isn't in the correct position. Call your provider if you aren't able to feel your implant on the inside of your upper arm.
                        How is Nexplanon (etonogestrel) inserted?
                        Your healthcare provider will place Nexplanon (etonogestrel) under the skin of the inner side of your upper arm using a needle. The procedure should take a few minutes.
                        How is Nexplanon (etonogestrel) removed?
                        Your healthcare provider can remove Nexplanon (etonogestrel) any time within 3 years after it was placed. This is usually done in their office. Your provider will first put some numbing medication around the area where Nexplanon (etonogestrel) was inserted. Then, they'll make a small cut in your arm and gently remove the implant with forceps. After it has been removed, they'll close your wound and place a bandage. While you can remove the top bandage after 24 hours, you'll need to keep the wound closure adhesive on for 3 to 5 days.
                        Does Nexplanon (etonogestrel) cause weight gain?
                        People who took Nexplanon (etonogestrel) in clinical studies did report weight gain as a side effect. People typically gain an average of 3 to 4 pounds after having Nexplanon (etonogestrel) in place for 1 to 2 years. A small group of people stopped using Nexplanon (etonogestrel) because of weight gain. But it's unclear whether the weight gain was caused by the implant, or other reasons. If you do gain weight, it could be because your body is holding onto water and you might feel bloated. If you notice that you have gained a lot of weight since starting on Nexplanon (etonogestrel), let your provider know.
                        Does Nexplanon (etonogestrel) cause acne?
                        Acne is one of the most common side effects of Nexplanon (etonogestrel), so there's a good chance this might happen to you. Most acne caused by this medication is mild and can be treated with over-the-counter products. If your acne becomes severe or is too bothersome for you, let your provider know so you can discuss alternatives.
                        How soon can you get pregnant after Nexplanon (etonogestrel) removal?
                        While the answer to this question is unique for everyone, it's possible to conceive as early as one week after having Nexplanon (etonogestrel) removed. If you're not sure whether you want to get pregnant after Nexplanon (etonogestrel) removal, make sure to use a condom.
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                        warings-icon

                        What are the risks and warnings for Nexplanon (etonogestrel)?

                        Nexplanon (etonogestrel) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

                        risk-warning

                        Problems during insertion and removal

                        Nexplanon (etonogestrel) will be implanted just below the skin, so you can feel it through the skin at all times. If Nexplanon (etonogestrel) is inserted too deeply, it can damage the muscles, tissues, and blood vessels around it. It can also lead to unwanted pregnancies. Very rarely, implants that have been inserted too deeply can move to another part of the body and cause infections. If Nexplanon (etonogestrel) has been placed incorrectly, your provider will need to be removed and placed again. If there's ever a time you can't feel the implant, contact your provider right away and use a barrier method of protection (e.g., condoms, diaphragms) to prevent pregnancy until your provider confirms the implant is in the right place.

                        risk-warning

                        Irregular periods

                        Nexplanon (etonogestrel) can commonly cause a change from your normal menstrual bleeding pattern, such as an absent period, spotting, or longer periods. If you're concerned with your menstrual cycle changes, talk with your provider. Most of the time, the kind of menstrual period you experience within the first 3 months after Nexplanon (etonogestrel) is placed is likely what will you'll continue to experience as long as the implant is in place.

                        risk-warning

                        Ectopic pregnancy or ovarian cyst

                        If you happen to get pregnant while taking Nexplanon (etonogestrel), there's a small chance that the pregnancy may be ectopic (outside of the womb). Additionally, Nexplanon (etonogestrel) can raise the risk of ovarian cysts (small sacs of fluid in the ovary). Although they rarely cause problems and tend to go away without any treatment, contact your provider if you ever have serious pain in your stomach area so they can check you for an ovarian cyst or ectopic pregnancy.

                        risk-warning

                        Blood clots

                        • Risk factors: History of blood clots | Having Nexplanon (etonogestrel) placed less than 21 days after giving birth | Medical problems or surgical procedures causing you to be bed-bound for a long time

                          There have been reports of blood clots in people using birth controls containing both estrogen and progestin. Blood clots can be very dangerous and lead to a heart attack, a stroke, or a pulmonary embolism (life-threatening blood clot in the lungs). Nexplanon (etonogestrel) only contains progestin, so it's unclear whether or not it carries the same risk for blood clots as combination birth controls. If you've ever had blood clots in the past, ask your provider whether Nexplanon (etonogestrel) is a good option for you.

                          In addition, you shouldn't get Nexplanon (etonogestrel) implanted if it has been less than 3 weeks since you delivered a baby because you're at a higher risk for getting blood clots during this time. Be sure to discuss all your past and present medical conditions with your provider before starting Nexplanon (etonogestrel). If you need to have surgery that will make it difficult for you to move much, ask your surgeon if you should have the implant removed before your procedure is done. Call 911 or get medical attention right away if you have pain in your legs or arms, chest pain, sudden severe headaches, trouble breathing, or sudden changes in your speech or vision.

                          risk-warning

                          Possible risk of cancer

                          • Risk factors: Personal or family history of breast cancer

                            Experts aren't sure if there's a higher risk of developing breast cancer from using combination birth control. But there are some cancer types that are sensitive to hormones in the birth controls. Because of this, people who have ever had breast cancer or have a strong family history of breast cancer should talk to their provider before using Nexplanon (etonogestrel) to see if this birth control is a good option for them. Remember to perform monthly breast self-exams and tell your provider about any changes you notice.

                            risk-warning

                            Future fertility

                            Nexplanon (etonogestrel) wears off quickly after it has been removed. Most people will begin to ovulate again within 2 weeks of removal, meaning you can become pregnant during your first menstrual cycle off Nexplanon (etonogestrel). Be sure to switch to a different form of birth control or use a backup method of protection (e.g., condoms, diaphragms) as soon as you have Nexplanon (etonogestrel) removed to prevent unwanted pregnancies.

                            risk-warning

                            Liver problems

                            If you experience symptoms of liver problems like yellowing of the skin or eyes, pain in the right upper stomach, or dark urine, stop using Nexplanon (etonogestrel) and contact your provider right away. It's unclear whether Nexplanon (etonogestrel) can raise your risk for tumor in the liver. But people with liver problems and liver cancer shouldn't use Nexplanon (etonogestrel).

                            risk-warning

                            High blood pressure

                            If you've blood pressure that isn’t under control or within blood pressure goals, don’t use Nexplanon (etonogestrel). If you're taking medications to control your blood pressure, your provider might ask you to monitor your blood pressure regularly to make sure it doesn’t get unusually high. Most times, there aren't any obvious symptoms of high blood pressure. But if you notice changes in your vision, headache, a racing heart, or flushing, call your provider immediately.

                            risk-warning

                            High blood sugar and cholesterol levels

                            Nexplanon (etonogestrel) can raise your sugar and cholesterol levels in the blood. If you have a history of having high blood sugar, your provider might need to check your blood sugar levels more often to make sure they don’t get unusually high.

                            risk-warning

                            Weight gain

                            Nexplanon (etonogestrel) can cause you to gain weight. You can keep track of your weight after you've started this medication. If you're gaining weight too much too fast, talk with your provider and they can discuss with you about other options for birth control.

                            risk-warning

                            Gallbladder problems

                            • Risk factors: History of gallbladder condition

                              Though rare, Nexplanon (etonogestrel) might cause new or worsening gallbladder problems. Tell your provider if you’ve had gallbladder problems in the past so they can monitor you more closely. Get medical help if you experience any of the following symptoms so your provider can check your gallbladder: yellowing of the skin or eyes, fever, chills, nausea or vomiting with severe pain in the right upper stomach, dark urine, or light-colored stools.

                              risk-warning

                              Vision changes

                              • Risk factors: Wearing contact lens

                                Let your provider know if you experience any vision changes after starting Nexplanon (etonogestrel). If so, you might need to have your vision checked by a specialist.

                                dosage

                                Nexplanon (etonogestrel) dosage forms

                                Typical dosing for Nexplanon (etonogestrel)

                                Nexplanon (etonogestrel) is placed under your skin in your upper arm by your healthcare provider at their office. Once placed, it can prevent pregnancy for up to 3 years.

                                interactions

                                Interactions between Nexplanon (etonogestrel) and other drugs

                                Nexplanon (etonogestrel) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Nexplanon (etonogestrel). Please note that only the generic name of each medication is listed below.

                                Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

                                Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                                Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                                Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                                contraindications-icon

                                Nexplanon (etonogestrel) contraindications

                                Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Nexplanon (etonogestrel) will not be safe for you to take.
                                • Pregnancy

                                • History of breast cancer or other progestin-sensitive cancer

                                • Have bleeding between your periods of which the cause hasn't yet been diagnosed by your provider

                                • History of blood clots or clotting disorders

                                • Have liver tumor, either benign or cancerous

                                • Acute (sudden) liver disease

                                alternatives

                                What are alternatives to Nexplanon (etonogestrel)?

                                There are a number of medications that your doctor can prescribe in place of Nexplanon (etonogestrel). Compare a few possible alternatives below.
                                Nexplanon (etonogestrel)
                                Used for:
                                • To prevent pregnancy

                                Used for:
                                • To prevent pregnancy

                                $21.77 Lowest GoodRx priceView Prices
                                Used for:
                                latest news

                                What is the latest news about Nexplanon (etonogestrel)?

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                                Nexplanon (etonogestrel) images

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                                This medicine is White Implant.white - Nexplanon 68mg Contraceptive Implant

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                                References

                                Best studies we found

                                Centers for Disease Control and Prevention. (2023). Contraception.

                                Centers for Disease Control and Prevention. (2023). Implants.

                                Edwards, M., et al. (2023). Progestin. StatPearls.

                                View All References (4)

                                Organon LLC. (2023). Nexplanon- etonogestrel implant [package insert]. DailyMed.

                                Reed, S., et al. (2023). Pregnancy and pregnancy outcomes in a prospective cohort study: Final results from the Nexplanon Observational Risk Assessment Study (NORA). Contraception.

                                Tholey, D. (2023). Cholestasis. Merck Manual Consumer Version.

                                You and Your Hormones. (2021). Progesterone.

                                GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.
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