Key takeaways
Nifedipine (Procardia XL) and verapamil (Calan) are both calcium channel blockers (CCBs) used to treat high blood pressure and chest pain (angina). However, they have some key differences. Nifedipine is a dihydropyridine CCB that primarily works by relaxing blood vessels, while Verapamil is a non-dihydropyridine CCB that also slows the heart rate, making it useful for treating arrhythmias. Nifedipine is available in both extended-release (ER) and immediate-release (IR) forms, with the ER form taken once daily and the IR form taken three to four times a day. Verapamil, on the other hand, is typically taken three to four times a day. Common side effects of Nifedipine include swelling in the legs, dizziness, and headaches, whereas Verapamil can cause constipation, dizziness, and nausea. Both medications are available in lower-cost generic forms.
