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Magnesium sulfate vs. Magnesium citrate

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Magnesium sulfate and magnesium citrate are both medications that contain magnesium and are used to treat different conditions. Magnesium sulfate is an electrolyte given by injection, often in hospitals, to treat low magnesium levels and prevent seizures in preeclampsia-eclampsia. It is also used off-label for conditions like torsades de pointes and severe asthma exacerbations. On the other hand, magnesium citrate, available under the brand name Citroma, is an oral saline laxative used to relieve occasional constipation. Magnesium sulfate is prescription-only, while magnesium citrate is available over-the-counter. Magnesium sulfate is generally well-tolerated with few side effects, such as flushing or low blood pressure if administered too quickly. In contrast, magnesium citrate can cause nausea, stomach pain, and diarrhea. Both medications should be used cautiously if you have kidney problems or electrolyte imbalances. Additionally, magnesium citrate can interact with other medications, so it's important to separate its use from other medications by at least two hours.

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Summary for Magnesium sulfate

Prescription only

Magnesium sulfate is typically used in the hospital to treat or prevent low magnesium levels. It's also used to prevent and manage seizures in preeclampsia-eclampsia (a complication of pregnancy). Additionally, magnesium sulfate may be used for other conditions. It's a generally well-tolerated medication and usually given as an injection by a healthcare provider.

Pros and Cons for Magnesium sulfate

Pros

Cons

Summary for Magnesium citrate

Over-the-counter

Magnesium citrate is a oral laxative solution that can ease the occasional constipation. It's available over the counter (OTC) and can help produce a bowel movement in 30 minutes to 6 hours. Magnesium citrate might not be a safe option if you have kidney problems or electrolyte levels that are out of balance.

Indications for Magnesium citrate

  • Occasional constipation

Pros and Cons for Magnesium citrate

Pros

  • Works fast, produces a bowel movement within 30 minutes to 6 hours
  • Available OTC without a prescription
  • Comes in different flavors
  • Many generic products available

Cons

  • Only for use with occasional constipation
  • Might not be a good option for people with kidney problems or those who need to limit magnesium or sodium intake
  • Can cause nausea and vomiting
  • Needs to be separated from other medications

Common Side Effects for Magnesium citrate

Warnings for Magnesium citrate

  • Complete or partial blockage of intestines
  • Kidney and other health conditions

Prices with our coupons for Magnesium sulfate vs. Magnesium citrate

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Magnesium Sulfate1 vial / 2ml of 1g/2ml
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Magnesium Citrate1 bottle / 296ml
$10.90-
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