Compare Imfinzi vs. Keytruda
Head-to-head comparisons of medication uses, side effects, warnings, and more.
- Imfinzi (durvalumab)Keytruda (pembrolizumab)
- Imfinzi (durvalumab)Keytruda (pembrolizumab)
Summary of Imfinzi vs. Keytruda
Summary for PD-L1 inhibitorPrescription onlyImfinzi (durvalumab) is a type of immunotherapy called an immune checkpoint inhibitor. It's used to treat a variety of cancers, such as certain types of lung cancer, liver cancer, bile duct cancer, and endometrial cancer. Imfinzi (durvalumab) is often given along with other immunotherapy or chemotherapy medications. Imfinzi (durvalumab) is infused into the veins by a trained member on your oncology team. It's usually given every 2 to 4 weeks, depending on the type of cancer. Imfinzi (durvalumab) can cause rare, but serious immune-related side effects including rash, breathing problems, and diarrhea.
Summary for PD-1 inhibitorPrescription onlyKeytruda (pembrolizumab) is an immunotherapy medication that’s used to treat many different types of cancer, including non-small cell lung cancer (NSCLC), breast cancer, and melanoma. This medication turns on your immune system so it can attack cancer cells. It's given as an intravenous (IV) infusion at a medical office or infusion center. Sometimes, Keytruda (pembrolizumab) can cause side effects, like diarrhea, rash, and trouble breathing, that might need to be treated with corticosteroids. Depending on the cancer, your treatment plan can consist of Keytruda (pembrolizumab) by itself or with other anticancer therapy.
Indications of Imfinzi vs. Keytruda
Indications for•Non-small cell lung cancer (NSCLC):•NSCLC that can be removed by surgery (with chemotherapy before surgery, or alone after surgery)•NSCLC that can't be removed by surgery (after platinum-based chemotherapy and radiation)•Metastatic NSCLC without EGFR or ALK mutations (with Imjudo (tremelimumab) and platinum-based chemotherapy)•Locally advanced or metastatic biliary tract cancer (with gemcitabine (Gemzar) and cisplatin (Platinol))•Advanced liver cancer (with Imjudo (tremelimumab))•Advanced endometrial cancer (with certain chemotherapy medications)Indications forCertain types of:
•Non-small cell lung cancer (NSCLC)•Renal cell carcinoma (kidney cancer)•Endometrial carcinoma (uterine cancer)•Cancers with high tumor mutation burden (TMB-H), high microsatellite instability (MSI-H), or deficient mismatch repair (dMMR)Pros and Cons of Imfinzi vs. Keytruda
Pros and Const for PD-L1 inhibitorPros•Possible treatment option for various cancers, including NSCLC, biliary tract cancer, and liver cancer•Lasts a long time in the body, so only need one infusion every 3-4 weeks•Uses your own immune system to attack the cancerCons•Commonly causes fatigue and rash•Can cause rare but serious immune-related side effects•Might require additional treatment to manage immune-related side effectsPros and Const for PD-1 inhibitorPros•Recommended first-choice treatment for many types of cancers under certain situations•Less likely to cause nausea, vomiting, and hair loss (side effects that are common with traditional chemotherapy)•Given every 3 or 6 weeks, depending on the treatment plan•Uses your own immune system to attack cancer cellsCons•Given as an injection through the veins•Might cause immune-related side effects like diarrhea, rash, and lung problems•Though rare, can cause infusion reactions•Might require you to take a break from treatment and take a corticosteroid to manage side effectsCommon Side Effects of Imfinzi vs. Keytruda
Common Side Effects for•Higher blood sugar levels (52%)•Lower blood calcium levels (46%)•Lower white blood cell counts (43%)•Cough (40%)•Higher liver lab tests (up to 39%)•Trouble breathing and symptoms of lung inflammation (34%)•Feeling very tired (34%)•Lower blood sodium levels (33%)•Higher blood potassium levels (32%)•Sore throat, runny nose, and other symptoms of colds and sinus infections (26%)•Trouble catching your breath (25%)•Rash (23%)Common Side Effects for•Higher blood sugar (52%)•Anemia (43%)•Higher liver enzyme levels (up to 33%)•Electrolyte changes in blood (up to 31%)•Lower white blood cells (30%)•Tiredness (25%)•Lower appetite (17%)•Trouble breathing (17%)•Cough (16%)•Rash (15%)•Diarrhea (12%)•Constipation (12%)•Nausea (12%)Warnings of Imfinzi vs. Keytruda
Common Side Effects for•Immune-related adverse events•Infusion-related reactions•Stem cell transplant complications•Harm to the unborn babyCommon Side Effects for•Immune-related side effects•Infusion-related reactions•Complications from stem cell transplants•Harm to unborn babyPrices with our coupons for Imfinzi vs. Keytruda
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