Key takeaways
Erleada (apalutamide) and Nubeqa (darolutamide) are medications that treat certain types of prostate cancer. They work by blocking testosterone, which helps slow or stop the growth of prostate cancer. Both medications are used for non-metastatic castration-resistant prostate cancer and metastatic hormone-sensitive prostate cancer. However, they differ in their dosing schedules and administration. Erleada is taken once a day, with or without food, while Nubeqa is taken twice a day with food. Common side effects of Erleada include tiredness, joint pain, and rash, while Nubeqa can cause low white blood cell count, tiredness, and rash. Nubeqa may may have fewer brain-related side effects compared to Erleada. But Nubeqa also has more drug interactions to consider.
