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Compare Erleada vs. Nubeqa

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Erleada (apalutamide)
    Nubeqa (darolutamide)
  • Erleada (apalutamide)
    Nubeqa (darolutamide)

  • Summary of Erleada vs. Nubeqa

    Summary for Androgen receptor inhibitor
    Prescription only

    Erleada (apalutamide) is a prescription pill used to treat certain types of prostate cancer in adults. It’s usually taken along with other hormone treatments or after you’ve had surgery to remove the testicles. You take it once a day by mouth, with or without food. Erleada (apalutamide) works by blocking testosterone, which helps slow the growth of prostate cancer. Common side effects include tiredness, joint pain, and rash.

    Summary for Androgen receptor inhibitor
    Prescription only

    Nubeqa (darolutamide) is a prescription medication used to treat certain types of prostate cancer in adults. You usually take it along with other hormone treatments, with chemotherapy, or after surgery to remove the testicles. As an androgen receptor inhibitor, it blocks testosterone from helping prostate cancer grow. You take the tablet by mouth twice a day with food. Common side effects include low white blood cell count, tiredness, and rash.

  • Indications of Erleada vs. Nubeqa

    Indications for
    •Metastatic prostate cancer that's hormone-sensitive
    •Non-metastatic prostate cancer that's castration-resistant
    Indications for
    •Non-metastatic prostate cancer that's castration-resistant
    •Metastatic prostate cancer that's hormone-sensitive, taken alone
    •Metastatic prostate cancer that's hormone-sensitive, used together with a chemotherapy medication called docetaxel

  • Pros and Cons of Erleada vs. Nubeqa

    Pros and Const for Androgen receptor inhibitor
    Pros
    •Pill that’s taken by mouth once a day
    •Recommended option for certain types of prostate cancer
    •Can take with or without food
    Cons
    •Can cause a rash, which can take several months to go away
    •Can raise your risk for seizures and fractures
    •Requires regular blood tests and monitoring
    Pros and Const for Androgen receptor inhibitor
    Pros
    •Available as a pill you take by mouth
    •Recommended option for certain types of prostate cancer
    •Might cause fewer brain-related side effects than similar medications
    Cons
    •Need to take it twice a day
    •Must take your dose with food
    •Can interact with many medications and products

  • Common Side Effects of Erleada vs. Nubeqa

    Common Side Effects for

    Metastatic prostate cancer:

    •Rash (28%)
    •Hot flashes (23%)
    •High blood pressure (18%)
    •Join pain (17%)
    •Itchiness (11%)

    Non-metastatic prostate cancer:

    •Tiredness (39%)
    •Rash (25%)
    •High blood pressure (25%)
    •Diarrhea (20%)
    •Nausea (18%)
    •Joint pain (16%)
    •Weight loss (16%)
    •Fall (16%)
    •Hot flashes (14%)
    •Fracture (12%)
    •Reduced appetite (12%)
    •Swelling in arms and legs (11%)
    Common Side Effects for

    Non-metastatic prostate cancer:

    •Rise in liver enzymes (up to 23%)
    •Lower white blood cell count (20%)
    •Tiredness (16%)

    Metastatic prostate cancer (when taken alone):

    •Rise in liver enzymes (up to 32%)
    •Lower white blood cell count (16%)

    Metastatic prostate cancer (when taken with docetaxel):

    •Lower red blood cell count (72%)
    •Higher blood sugar levels (57%)
    •Lower white blood cell count (up to 52%)
    •Rise in liver enzymes (up to 40%)
    •Low calcium levels (31%)
    •Constipation (23%)
    •Rash (20%)

  • Warnings of Erleada vs. Nubeqa

    Common Side Effects for
    •Heart attack and stroke
    •Falls and fractures
    •Seizures
    •Severe skin reactions
    •Lung problems
    •Harm to unborn baby
    Common Side Effects for
    •Heart problems
    •Seizure
    •Harm to unborn baby

  • Prices with our coupons for Erleada vs. Nubeqa

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