Most androgen-receptor inhibitors are used to treat prostate cancer. One is used to treat acne. These medications work by blocking the effects of androgens, which are male hormones that can promote the growth of cancer cells or cause other unwanted effects. Androgen-receptor inhibitors come in different forms, including oral pills and topical creams. Examples include bicalutamide (Casodex), nilutamide (Nilandron), and Winlevi (clascoterone)