Key takeaways
Methylprednisolone (Medrol) and dexamethasone (Ozurdex) are both corticosteroids that can be used to treat eye inflammation, but they differ in their specific uses and forms. Methylprednisolone is available as oral tablets and injections and also treats a wide range of conditions, including joint issues, lupus, and allergic reactions. Dexamethasone, on the other hand, is used as an ophthalmic implant to treat eye conditions like diabetic macular edema and inflammation in the back of the eye. While methylprednisolone is available as a lower-cost generic, dexamethasone (Ozurdex) is only available as a brand-name medication. Methylprednisolone can cause side effects like weight gain and high blood sugar, while dexamethasone may lead to eye-related side effects such as increased eye pressure and retinal detachment.
