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Claritin vs. Sudafed

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Loratadine (Claritin) and pseudoephedrine (Sudafed) are both over-the-counter medications, but they serve different purposes and belong to different drug classes. Loratadine is an antihistamine used to relieve allergy symptoms like runny nose and itchy eyes. It is typically taken once daily and is less likely to cause drowsiness compared to other antihistamines. On the other hand, pseudoephedrine is a decongestant that helps relieve nasal and sinus congestion. It works by narrowing blood vessels in the nasal passages and is available in both short-acting and extended-release forms. While loratadine is generally safe for children as young as 2 years old, pseudoephedrine is not recommended for children under 4 years old. Additionally, pseudoephedrine can raise blood pressure and heart rate, making it unsuitable for people with certain health conditions. Loratadine is not likely to cause these cardiovascular side effects. Both medications should be used with caution to avoid accidental overdose, especially since they can be found in many combination products.

Loratadine

(Claritin)

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Sudafed

(pseudoephedrine)

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Summary for Claritin

Over-the-counter

Loratadine (Claritin) is an over-the-counter antihistamine for adults and kids. It helps relieve allergy symptoms like a runny nose, sneezing, and watery eyes. This allergy medication is taken by mouth, usually once a day. It comes as different formulations, including regular tablets, chewable tablets, and a liquid. Loratadine (Claritin) is a non-drowsy allergy medication because it's less likely to make you sleepy. Other side effects can include headache and feeling tired. Loratadine (Claritin) is available as a brand-name and generic.

Indications for Claritin

  • Short-term relief of allergy symptoms (runny nose, itchy nose or throat, itchy or watery eyes)

Pros and Cons for Claritin

Pros

Cons

  • Can take 1 to 3 hours to start working
  • Regular tablets and quick-dissolving tablets not for children younger than 6
  • Might have a higher risk of side effects if you have liver or kidney problems

Common Side Effects for Claritin

  • Headache (12%)
  • Sleepiness (8%)
  • Feeling tired (4%)
  • Dry mouth (3%)

Warnings for Claritin

  • Sleepiness
  • Accidentally taking too much medication
  • Caution use in people with phenylketonuria (PKU) - chewable tablets and orally disintegrating tablets

Summary for Sudafed

Over-the-counter

Sudafed (pseudoephedrine) is a non-drowsy decongestant taken by mouth to treat nasal and sinus congestion from allergies and the common cold. It's available in a short-acting version that's taken once every 4 to 6 hours. It also comes in longer-acting versions that are taken every 12 or 24 hours, depending on the dose. Side effects of Sudafed (pseudoephedrine) include anxiety and headache. This medication might also keep you awake at night if you take it too close to bedtime. Sudafed (pseudoephedrine) is an OTC medication, but it's restricted, so you can only purchase it at the pharmacy counter.

Indications for Sudafed

  • Short-term relief of nasal and sinus congestion and pressure

Pros and Cons for Sudafed

Pros

  • Works well to treat congestion
  • Available in longer-acting versions that last 12 hours or 24 hours
  • Children's oral liquids can be taken by kids as young as 4 years old
  • Available as lower-cost generics

Cons

  • Several products have different age cut-offs for use in children, so can be confusing
  • Might make it hard for some people to sleep
  • Can raise blood pressure and heart rate
  • Not recommended during pregnancy

Common Side Effects for Sudafed

  • Sweating
  • Nervousness
  • Excitability
  • Difficulty sleeping
  • Low appetite
  • Difficulty urinating

Warnings for Sudafed

  • Fast heart rate and high blood pressure
  • Worsening of medical conditions
  • Accidental overdose

Prices with our coupons for Claritin vs. Sudafed

Price Card Drug Icon
Loratadine30 tablets / 24 hour
$8.59$8.93
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Pseudoephedrine24 tablets / 30mg
$10.68-
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