Key takeaways
Loratadine (Claritin) and fluticasone (Flonase) are both used to treat allergy symptoms, but they work in different ways and come in different forms. Loratadine is an antihistamine taken by mouth, available over-the-counter in various forms like tablets and liquids. It helps relieve symptoms like runny nose and itchy eyes by blocking histamine, a chemical in your body that causes allergies. On the other hand, fluticasone is a corticosteroid nasal spray that reduces inflammation in your nose, helping with symptoms like congestion and sneezing. Fluticasone is available both by prescription and over-the-counter, and it must be used daily for the best results. While loratadine is less likely to cause drowsiness compared to older antihistamines, fluticasone can cause side effects like nosebleeds and, in children, slower growth if used for long periods. Additionally, fluticasone can raise the risk of certain eye problems and infections, which is not a concern with loratadine.
