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Brexafemme vs. Fluconazole

Brexafemme (ibrexafungerp) is an antifungal that's used to treat vaginal yeast infections in adults and children who've started having menstrual periods. This medication can also help lessen the risk of having a vaginal yeast infection again. In general, the dose is 2 tablets by mouth twice a day for 1 day. Side effects of Brexafemme (ibrexafungerp) include diarrhea, nausea, and stomach pain. This medication has a risk of harming an unborn baby.

• Treatment of vaginal yeast infection
• Lessen the occurrence of recurrent vaginal yeast infection

• Diarrhea (17%)
• Nausea (12%)
• Stomach pain (11%)

• Harm to an unborn baby

Fluconazole (Diflucan) is an azole antifungal. It's used to treat different types of Candida infections, such as vaginal yeast infections and oral thrush. It can also treat a serious brain infection called cryptococcal meningitis. Oral fluconazole (Diflucan) is available as a tablet and suspension. It's taken by mouth as a one-time dose for vaginal yeast infections; it's typically taken once daily for other types of infections. Fluconazole (Diflucan) is generally well-tolerated, but some people can experience side effects like headache, nausea, and stomach pain. Fluconazole (Diflucan) can raise the risk of liver problems, so you're recommend to avoiding drinking alcohol while taking this medication.

• Treatment of infections caused by Candida:
  • Vaginal yeast infections
  • Mouth, throat, or esophagus infections, including oral thrush
  • Bloodstream infections
  • Urinary tract infections (UTIs)
  • Peritonitis (infection of the lining of the stomach)
  • Pneumonia
• Prevention of Candida fungal infections for people having a bone marrow transplant
• Cryptococcus meningitis

Single dose for vaginal yeast infection:

• Headache (13%)
• Nausea (7%)
• Stomach pain (6%)
• Diarrhea (3%)

Multiple doses for other infections:

• Nausea (4%)
• Headache (2%)
• Skin rash (2%)
• Vomiting (2%)
• Stomach pain (2%)
• Diarrhea (2%)

• Liver damage
• Allergic reaction
• Severe skin reaction
• Harm to unborn babies