Key takeaways
Azelastine (Astepro Allergy) and fluticasone (Flonase) are both nasal sprays used to treat allergy symptoms like a runny nose and sneezing but there are some differences between them. They are available over-the-counter and can be used by adults and children, although the age limits differ. Azelastine is an antihistamine, while fluticasone is a corticosteroid. Azelastine works by blocking histamine to relieve symptoms, whereas fluticasone reduces inflammation in the nose. Azelastine is typically used once or twice a day, while fluticasone is used once daily. Azelastine can cause drowsiness and a bitter taste, while fluticasone may lead to nosebleeds and, in children, slower growth if used for more than two months. Fluticasone also has a risk of eye problems and infections with long-term use. Azelastine is not known to raise blood pressure, but fluticasone can increase the risk of certain eye problems and infections. Both medications should be used with caution if you have had recent nasal surgery or injury.
