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Amlodipine vs. Lisinopril

Amlodipine tablets, also known as the brand name Norvasc, help treat high blood pressure in adults and children. It can also help with coronary artery disease, including related angina or chest pain. This medication belongs to the drug class called calcium channel blockers. The tablets are taken by mouth once a day. Some side effects can include tiredness and swelling of the hands and feet.

• High blood pressure
• Coronary artery disease, including some types of chest pain (angina)

• Tiredness (5%)
• Nausea (3%)

• Low blood pressure
• Worsening chest pain and risk of heart attack

Lisinopril (Zestril) is an angiotensin-converting enzyme inhibitor, or ACE inhibitor. It's used to treat high blood pressure in people 6 years and older. In adults, it's also approved to manage heart failure and to lower the risk of death after a heart attack. Lisinopril (Zestril) comes as a tablet that's taken by mouth once daily. There's also an oral solution available under the brand name Qbrelis. Some side effects include dizziness, cough, and headache.

• High blood pressure in people ages 6 years and older
• Heart failure in adults
• Lowering the risk of death after a heart attack in adults

• Dizziness (up to 19%)
• Low blood pressure (up to 11%)
• Higher creatinine levels (up to 10%)

• Harm to an unborn baby
• Angioedema (swelling)
• Low blood pressure
• Possible worsening of kidney problems
• High potassium levels
• Liver problems