NSAID / Prostaglandin Combinations

NSAID / prostaglandin combinations are used to treat osteoarthritis and rheumatoid arthritis. The NSAID relieves pain and inflammation while the prostaglandin protects the stomach and duodenum (small intestine) from developing ulcers.

Why are nsaid prostaglandin combinations prescribed?

Osteoarthritis (50%)
Rheumatoid Arthritis (50%)

How are these percentages calculated?

Key takeaways

Nonsteroidal anti-inflammatory drug (NSAID) / prostaglandin combinations are used to treat osteoarthritis and rheumatoid arthritis for people who have a high risk of stomach ulcers. These medications work by combining an NSAID to reduce pain and inflammation with a prostaglandin to protect the stomach lining from irritation and ulcers caused by the NSAID. They are available as oral tablets. An example of this combination is diclofenac / misoprostol (Arthrotec).

Prices for popular NSAID / Prostaglandin Combinations medications

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Arthrotec (diclofenac sodium/misoprostol)

as low as$50

DICLOFENAC; MISOPROSTOL treats arthritis in people at risk of stomach ulcers from taking NSAID medications. Diclofenac works by decreasing pain and inflammation. Misoprostol works by reducing the amount of acid in the stomach and protecting the stomach lining from irritation. This medication is a combination of an NSAID and a prostaglandin.

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Disclaimer: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.