Lincosamide / retinoid / antiseptic combinations are used to treat acne. These medications work by combining the antibacterial properties of lincosamides, the skin-renewing effects of retinoids, and the germ-killing action of antiseptics to reduce inflammation and clear up acne. These combinations are typically available in topical forms, such as gels, making them easy to apply directly to the affected area. An example includes Cabtreo (clindamycin / tretinoin / benzoyl peroxide). You can use these treatments to help improve your skin health and appearance.