Coagulation factors are used to treat hemophilia, von Willebrand disease, and other bleeding conditions. These medications work by replacing the missing or deficient clotting factors in your blood, helping it to clot properly and prevent excessive bleeding. Coagulation factors are typically available as injectable forms. Examples include factor VIII (Advate), factor IX (Benefix), and factor XIII (Tretten). You can discuss with your healthcare team to determine the best option for your condition.