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Boostrix

Boostrix Side Effects

Robert Chad Hakim, PharmD, BCCCPCydnee Ng, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Cydnee Ng, PharmD
Last reviewed on March 13, 2026

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Pain at injection site (75%)
  • Headache (43%)
  • Tiredness (37%)
  • Nausea, vomiting, diarrhea, or stomach pain (26%)
  • Redness at injection site (23%)
  • Swelling at injection site (21%)
  • Fever (14%)

Less Common Side Effects

  • Rash
  • Muscle pain

Boostrix serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reaction: hives, rash, shaking, itching, nausea, flushing, dizziness, shortness of breath, chest pain
When do Boostrix possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Pain, redness, or swelling at injection site
Headache
Tiredness

Source: DailyMed

The following Boostrix side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Less common

Collapse or shock-like state

crying for 3 hours or more

fever over 102.2 °F

redness or swelling of 4 inches or more at the injection site

seizures (convulsions)

severe pain at the injection site

Incidence not known

Agitation

back pain

black, tarry stools

bleeding gums

bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

blood in the urine or stools

bloody nose

bluish color of the fingernails, lips, skin, palms, or nail beds

blurred vision

confusion

cough

diarrhea

difficulty with swallowing

dizziness

drowsiness

fast heartbeat

hallucinations

headache

hoarseness

irritability

irritation

joint pain, stiffness, or swelling

loss of bladder control

loss of consciousness

loss of strength or energy

muscle pain or weakness

nausea and vomiting

pain or cramping in the abdomen or stomach

pinpoint red spots on the skin

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

rash with flat lesions or small raised lesions on the skin

screaming

shortness of breath

sleepiness or unusual drowsiness

sneezing

sore throat

stiff neck

swollen, painful, or tender lymph glands in the neck, armpit, or groin

tightness in the chest

total body jerking

unusual bleeding or bruising

unusual tiredness or weakness (sudden and severe)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Fever of 99.5 °F or more

fussiness

loss of appetite

mild pain, redness, swelling, or tenderness at the injection site

restlessness

weight loss

Incidence not known

Crying

ear pain

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Cydnee Ng, PharmD
Reviewed by:
Cydnee Ng, PharmD
Cydnee Ng, PharmD, is a drug information pharmacist at GoodRx, where she lends her expertise to providing reader-friendly, accessible content about medications. She holds her pharmacist license in California.

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