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Menactra

Menactra Side Effects

Robert Chad Hakim, PharmD, BCCCPAllison Gourley, PharmD
Reviewed by Robert Chad Hakim, PharmD, BCCCP, Allison Gourley, PharmD
Last reviewed on April 26, 2022

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

Side effects reported by adolescents across all 3 [[EDITOR|DRUG_DISPLAY_NAME]] (MenQuadfi, Menveo, and Menactra)

  • Pain at injection site (34-45%)
  • Feeling sluggish (11-35%)
  • Headache (27-30%)
  • Redness at injection site (5-15%)
  • Swelling at injection site (5-11%)

Less Common Side Effects

  • Vomiting
  • Fever
  • Diarrhea
  • Rash
  • Muscle pain
  • Joint pain
  • Low appetite

Menactra serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Serious allergic reactions: hives, rash, shaking, itching, nausea, flushing, dizziness, shortness of breath, chest pain
  • Breathing problems for premature babies (for Menveo only): not breathing for 15 or 20 seconds at a time, not breathing for less than 15 seconds at a time with slow heart rate

Source: DailyMed

The following Menactra side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Chills

fever

general feeling of discomfort or illness

unusual tiredness or weakness

Incidence not known

Back pain, sudden and severe

blurred vision

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

confusion

cough

difficulty with swallowing

dizziness

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

fainting

fast heartbeat

flushing or redness of the skin

hives or welts

inability to move the arms and legs

itching

muscle weakness, sudden and progressing

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

seizures

shortness of breath

skin rash

sudden numbness and weakness in the arms and legs

sweating

tightness in the chest

unusually warm skin

wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Crying

diarrhea

difficulty with moving

drowsiness

irritability

loss of appetite

muscle pain or stiffness

pain in the joints

pain, redness, swelling, or tenderness at the injection site

vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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Why trust our experts?

Robert Chad Hakim, PharmD, BCCCP, started his full-time career as a clinical pharmacist at UCLA Health in the general medicine, general cardiology, and ICU units after completing residency in 2016. He also was the preceptor for the general medicine rotation from 2017 to 2021, which was a required rotation for all pharmacy residents.
Allison Gourley, PharmD, is a kidney and pancreas transplant pharmacist at a teaching hospital in the San Francisco Bay Area. When she’s not educating patients about their immunosuppressants, she's actively involved in transplant research.

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