Relistor Tablets for Constipation Coming Soon

Roni Shye
Roni Shye, PharmD BCGP BCACP, is a licensed pharmacist in the states of Florida, Ohio, and Pennsylvania.
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Recently a new tablet form of Relistor was approved by the FDA. Relistor was previously available only as a subcutaneous injection—which may mean it will be easier to use for anyone who has an aversion to injections.

What is Relistor used for?

Like the injection, Relistor tablets are used to treat opioid-induced constipation (OIC) in adults with chronic non-cancer pain.

Opioid-induced constipation is a very specific type of constipation due to the use of opioids (Vicodin (hydrocodone/acetaminophen), Percocet (oxycodone/acetaminophen), Oxycotin (oxycodone), morphine, and codeine are all examples of opioid medications).

How are Relistor tablets taken?

The recommended dose of Relistor is three tablets ( total) taken once daily in the morning.

Relistor tablets should be taken with water on an empty stomach at least 30 minutes before your first meal of the day.

How will Relistor be available now?

Relistor will now be available as a tablet. There is also a prefilled syringe in /0.4 mL and /0.6 mL strengths, and a /0.6 mL vial for injection.

What are the side effects of Relistor?

The most common side effects associated with Relistor include stomach pain, diarrhea, headache, abdominal distention, excessive sweating, anxiety, muscle spasms, runny nose, and chills.


When will Relistor tablets be available?

Relistor tablets should be available soon. The manufacturer has estimated that they will be in pharmacies in the third quarter of 2016.


Want more information?

See the press announcement from the manufacturer Valeant and Progenics here.

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