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Meet Yuvafem, the New Generic to Vagifem Tablets

by Dr. Sharon Orrange on October 27, 2016 at 3:01 pm

Used for the treatment of vaginal dryness and recurrent urinary tract infections, among other things, Vagifem (estradiol) tablets have been a huge hit in the United States. As mentioned in my previous blog, patients prefer Vagifem tablets over Estrace vaginal cream—but one of the downsides of Vagifem has been cost. Yuvafem, a new generic equivalent just approved by the FDA, may finally give Vagifem competition—if it can save women some cash.

What’s Yuvafem?

  • Made by Amneal Pharmaceuticals, Yuvafem 10 mcg estradiol vaginal inserts are shipping to pharmacies this month.
  • Like Vagifem, Yuvafem tablets are used for the treatment for menopausal symptoms.
  • This is the first generic equivalent to Vagifem.
  • Yuvafem delivers the same low dose of vaginal estrogen as Vagifem in a preloaded, single-use, disposable applicator.
  • Yuvafem will come in packages of 8 or 18 tablets. It is used daily for the first two weeks, then twice weekly.
  • Like Vagifem, Yuvafem estradiol vaginal tablets are used for vaginal dryness, irritation, itching and soreness, as well as pain during intercourse and recurrent urinary tract infections.

Will Yuvafem be cheaper than Vagifem?

I hope so, but we don’t know yet. Vagifem made a startling $423 million dollars in the U.S. from July 2015 to July 2016 so it’s good to have a potentially cheaper equivalent.

Dr O.


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