Is Trulicity Better Than Victoza or Bydureon?

a doctor's prescription pad
Dr. Sharon Orrange
Dr. Orrange is an Associate Professor of Clinical Medicine in the Division of Geriatric, Hospitalist and General Internal Medicine at the Keck School of Medicine of USC.
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The newest of the injectable diabetes medications which also helped diabetics lose weight is Trulicity, just approved in September 2014. Given that Trulicity has a low incidence of hypoglycemia and mild gastrointestinal side effects it will become a good option for type II diabetics.

Is it better than the other new diabetes meds?

Trulicity lowered Hgb A1C slightly more than, or the same as, Bydureon, Victoza, and the oral pills Januvia and metformin (Glucophage). Remember that Victoza is a once a day injection instead of once a week for Bydureon and Trulicity.

How does it work?

Trulicity is a glucagonlike peptide-1 (GLP-1) analog that works to increase insulin secretion in the presence of high blood glucose. It will not work if sugars are low thus, unlike with insulin, there is almost no risk of low sugars (hypoglycemia) with this injection medication.

How do I use it?

It’s an injection under the skin given once a week at a dose of 0.75 mg. The dose may be increased to 1.5 mg once weekly if you need better control of your sugars. Trulicity is available in a ready-to-use pen device with an automatic injector.

Will I lose weight?

Yes, a modest weight loss of 3 kilograms (6.6 pounds) was seen in patients on Trulicity.

Dr O.

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