What is the downside of Trulicity?

Everyone's experience with Trulicity is different. But many people are able to use it without major problems. Common Trulicity side effects include nausea, diarrhea, and stomach pain. Indigestion and fatigue are also possible. Many of these side effects may improve as your body gets used to the medication. Trulicity has been linked to gallbladder disease in some people taking it. This can include gallstones and gallbladder inflammation (cholecystitis).