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Anagrelide Coupon - Anagrelide 0.5mg capsule

anagrelide

Generic Agrylin
Used for Thrombocythemia
Used for Thrombocythemia

Anagrelide (Agrylin) is a good medication for people who have a high number of platelets. It can cause side effects so it should be used with caution in people with certain heart and liver conditions.

Reviewed by:
reviewer
Hope Chang, PharmD, AAHIVP
reviewer
Michelle Nguyen, PharmD
Last reviewed on August 12, 2021
BasicsSide effectsPros & consPharmacist tipsFAQsWarningsDosageInteractionsCostAlternativesImagesPricesMedicare
basics-icon

What is Anagrelide (Agrylin)?

What is Anagrelide (Agrylin) used for?

  • Thrombocythemia (high number of platelets)

How Anagrelide (Agrylin) works

Anagrelide (Agrylin) is an antiplatelet medication. While the exact mechanism isn't known, it's slows down the body's ability to make platelets in order to thin your blood.

Drug Facts

Common BrandsAgrylin
Drug ClassAntiplatelet
Controlled Substance ClassificationNot a controlled medication
Generic StatusLower-cost generic available
AvailabilityPrescription only
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Avg retail price
$416.67(save 37.71%)
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$259.55
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What are the side effects of Anagrelide (Agrylin)?

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Headache (44%)
  • Abnormal heart beat (26%)
  • Diarrhea (26%)
  • Weakness or lack of energy (23%)
  • Swelling and holding onto fluid (21%)
  • Nausea (17%)
  • Abdominal pain (16%)
  • Dizziness (15%)
  • Shortness of breath (12%)

Other Side Effects

  • Vomiting
  • Gas
  • Fever
  • Loss of appetite
  • Rash
  • Cough
  • Pain

Serious Side Effects

Contact your healthcare provider immediately if you experience any of the following.
  • Chest pain

Source: DailyMed

The following side effects have also been reported

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Bloating or swelling of the face, arms, hands, lower legs, or feet

body aches or pain

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain

congestion

cough

difficult or labored breathing

dryness or soreness of the throat

fast, irregular, pounding, or racing heartbeat or pulse

fever

hoarseness

rapid weight gain

runny nose

tender, swollen glands in the neck

tightness in the chest

trouble with swallowing

voice changes

Less common

Anxiety

blurred vision

burning feeling while urinating

chills

cold sweats

confusion

decreased urine output

dehydration

difficult or painful urination

dilated neck veins

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

extreme tiredness or weakness

general feeling of discomfort or illness

headache

irregular breathing

joint pain

large, flat, blue, or purplish patches on the skin

loss of appetite

muscle aches and pains

nausea

noisy breathing

pale skin

redness of the face, neck, arms, and occasionally, upper chest

severe pain or pressure in the chest or the jaw, neck, back, or arms

sudden severe headache or weakness

swollen, painful, or tender lymph glands in the neck, armpit, or groin

trouble sleeping

troubled breathing with exertion

unusual bleeding or bruising

unusual tiredness or weakness

vomiting

vomiting of blood or material that looks like coffee grounds

weight gain

Incidence not known

Clay-colored stools

dark urine

decreased appetite

dry cough

general feeling of tiredness or weakness

rapid breathing

skin rash or itching

stomach pain or tenderness

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Back pain

belching

diarrhea

excess air or gas in the stomach or bowels

full feeling

heartburn

hives or welts

indigestion

lack or loss of strength

pain

passing gas

stomach discomfort, upset, or pain

Less common

Burning feeling in the chest or stomach

change in vision

constipation

continuing ringing or buzzing or other unexplained noise in the ears

depression

difficulty with moving

double vision

hair loss or thinning of the hair

hearing loss

impaired vision

increased sensitivity of the skin to sunlight

leg cramps

loss of memory

muscle pain or stiffness

problems with memory

redness or other discoloration of the skin

seeing double

severe sunburn

sleepiness or unusual drowsiness

stuffy nose

swelling or inflammation of the mouth

swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

pros-and-cons

Pros and cons of Anagrelide (Agrylin)

thumbs-up

Pros

Available as a generic, which can be less expensive

Dose can be easily adusted based on your platelet levels

Can be used in children age 7 and older

Can be used in people with kidney problems with no recommended dose changes

thumbs-down

Cons

Requires frequent monitoring

Should be avoided in people with severe liver problems and certain heart conditions

Causes more side effects than other medications like hydroxyurea

Usually needs to be taken more than once a day

pharmacist-tips

Pharmacist tips for Anagrelide (Agrylin)

pharmacist

  • Take this medication with or without food.

    • Antiplatelet medications like anagrelide (Agrylin) can make you bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.

      • If you do happen to cut yourself or fall, make sure that any cuts or bruises heal correctly. Contact your provider if a cut doesn't clot and continues to bleed or if your bruise gets larger over time.

        • Store anagrelide (Agrylin) at room temperature. Keep the medication in it's original container to protect it from light. If you use a pill box to help you take your medications, try to use one that's light-resistant.

          • Avoid taking anagrelide (Agrylin) with other medications that raise your risk of bleeding. These include other blood thinners, NSAIDs (ibuprofen, naproxen), and some antidepressants. If you're already taking some of these medications let your provider know. Don't stop taking any prescribed medications on your own.

            faqs

            Frequently asked questions about Anagrelide (Agrylin)

            Is anagrelide (Agrylin) a chemotherapy medication?
            No, anagrelide (Agrylin) is not considered a chemotherapy medication even though it is used in certain blood cancers.
            Is anagrelide (Agrylin) an anticoagulant?
            No, anagrelide (Agrylin) is not an anticoagulant. Medications that prevent blood clots belong to 2 different drug classes: 1) anticoagulants work against clotting factors and 2) antiplatelets lower the number of platelets in the body. Anagrelide (Agrylin) is an antiplatelet medication.
            Does anagrelide (Agrylin) cause anemia?
            Anemia was reported during clinical trials of anagrelide (Agrylin), but it's not a very common side effect.
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            What are the risks and warnings for Anagrelide (Agrylin)?

            Anagrelide (Agrylin) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.

            risk-warning

            Heart toxicity

            • Risk factors: History of heart problems | Prolonged QT interval or taking other medications that prolong QT interval | Liver problems | Low potassium

              There have been reports of people having heart problems or changes to their heartbeat while taking
              anagrelide (Agrylin). It's more likely to happen in people who have a history of heart problems or are at a higher risk for having them. Having severe liver problems can lead to higher levels of anagrelide (Agrylin), which can also raise your risk of having heart problems. Talk to you provider about your past medical history, including your heart health and all the medications you take.

              risk-warning

              Bleeding risk

              • Risk factors: Taking anagrelide (Agrylin) with other medications that increase bleeding (i.e., aspirin, anticoagulants, NSAIDs, antiplatelet agents, antidepressants)

                Taking anagrelide (Agrylin) with aspirin can raise your risk of a major bleed. Your risk might also be higher if you are taking other medications that raise your bleeding risk. Let your provider know all the medications you're taking so they can check for interactions. Always monitor for signs and symptoms of bleeding such as bruises that get bigger over time, bleeding gums, dark, tarry stools, and blood in your urine. Contact your provider right away if you notice any of these symptoms.

                risk-warning

                Lung Problems

                Serious lung conditions have been reported with anagrelide (Agrylin) and can happen at any time. Report any changes to your breathing, including worsening shortness of breath. If your provider suspects lung damage they might stop the medication, which can improve symptoms.

                dosage

                Anagrelide (Agrylin) dosage forms

                The average cost for 60 capsules of 0.5mg of Anagrelide (Agrylin) is $259.55 with a free GoodRx coupon. This is 37.71% off the average retail price of $416.67.
                capsule
                Capsule
                DosageQuantityPrice as low asPrice per unit
                0.5mg30 capsules$259.55$8.65

                Typical dosing for Anagrelide (Agrylin)

                • Adults: The typical starting dose is 0.5 mg by mouth four times a day or 1 mg twice a day.

                • Children: The typical starting dose is 0.5 mg by mouth once a day.

                interactions

                Interactions between Anagrelide (Agrylin) and other drugs

                Anagrelide (Agrylin) may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. The list below does not include all possible drug interactions with Anagrelide (Agrylin). Please note that only the generic name of each medication is listed below.

                Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

                Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

                drug-cost

                How much does Anagrelide (Agrylin) cost?

                To access savings, use a GoodRx coupon and pay just a fraction of the retail price.
                Agrylin (brand)
                GoodRx lowest price

                $259.55

                (save 67.98%)
                Anagrelide (Agrylin) (generic)
                GoodRx lowest price

                $259.55

                (save 37.71%)
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                alternatives

                What are alternatives to Anagrelide (Agrylin)?

                There are a number of medications that your doctor can prescribe in place of Anagrelide (Agrylin). Compare a few possible alternatives below.
                Anagrelide (Agrylin)
                Used for:

                • Thrombocythemia (high number of platelets)

                $259.55 Lowest GoodRx priceView Prices
                Hydroxyurea (Hydrea)
                Used for:

                • Chronic myeloid leukemia (CML)

                • Head and neck cancers (in combination with chemotherapy and radiation)

                $32.64 Lowest GoodRx priceView Prices
                Aspirin
                Used for:

                • Pain relief from minor aches and pains, such as from headaches, muscle pain, toothache, menstrual cramps, and arthritis

                • Fever

                • Heart protection (lower the risk for heart attack or stroke) in certain adults - low-dose aspirin (81 mg per day) only

                $2.80 Lowest GoodRx priceView Prices
                images

                Anagrelide (Agrylin) images

                Gray And White Logo 5241 0.5 Mg - Anagrelide Hydrochloride 0.5mg Capsule
                This medicine is Gray And White Capsule Imprinted With "Logo 5241 0.5 Mg".Gray And White Logo 5241 0.5 Mg - Anagrelide Hydrochloride 0.5mg Capsule
                Gray And White 1453 0.5 Mg - Anagrelide Hydrochloride 0.5mg Capsule
                This medicine is Gray And White Capsule Imprinted With "1453 0.5 Mg".Gray And White 1453 0.5 Mg - Anagrelide Hydrochloride 0.5mg Capsule
                White Ce 55 - Anagrelide Hydrochloride 0.5mg Capsule
                This medicine is White Capsule Imprinted With "Ce 55".White Ce 55 - Anagrelide Hydrochloride 0.5mg Capsule

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