Levocetirizine (Xyzal Allergy) is an antihistamine. It's used to relieve allergy symptoms and chronic hives in adults and children. Levocetirizine (Xyzal Allergy) is available both over the counter and by prescription, and comes as a tablet and a liquid. Your dosage can depend on your age. This medication is taken by mouth, typically once daily. Some side effects of levocetirizine (Xyzal Allergy) include drowsiness and the common cold-like symptoms.
Levocetirizine (Xyzal Allergy) is an antihistamine. It blocks histamine, a natural chemical in your body that can cause allergy symptoms like itchiness, itchy eyes, or runny nose. By blocking histamine, levocetirizine (Xyzal Allergy) helps relieve allergy symptoms.
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
People 12 years and older:
Children under 12 years old:
People 12 years and older:
Children under 12 years old:
Contact your healthcare provider immediately if you experience any of the following.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
attack, assault, or force
bloody, cloudy, or dark urine
blurred or loss of vision
burning feeling while urinating
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chills
clay-colored stools
confusion
decrease in the frequency of urination
decrease in urine volume
deep or fast breathing with dizziness
difficult or labored breathing
difficulty in passing urine (dribbling)
difficulty with swallowing or speaking
discouragement
disturbed color perception
dizziness, fainting, or lightheadedness when getting up suddenly from a lying or sitting position
double vision
fast, irregular, pounding, or racing heartbeat or pulse
feeling of constant movement of self or surroundings
feeling sad or empty
fixed position of the eye
general tiredness and weakness
halos around lights
headache
hives or welts, itching, skin rash
inability to move the eyes
increased blinking or spasms of the eyelid
irritability
joint or muscle pain
lack of appetite
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
light-colored stools
loss of balance control
loss of interest or pleasure
muscle trembling, twitching, jerking, or stiffness
nervousness
night blindness
numbness of the feet, hands, and around the mouth
overbright appearance of lights
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
redness of the skin
restlessness
rhythmic movement of the muscles
seeing, hearing, or feeling things that are not there
seizures
sensation of spinning
shaking
shuffling walk
sticking out of the tongue
stomach pain
swelling of the face, feet, or lower legs
thoughts of killing oneself
tightness in the chest
trouble concentrating
trouble with sleeping
tunnel vision
twisting movements of the body
uncontrolled movements, especially of the face, mouth, tongue, neck, and back
uncontrolled twisting movements of the neck, trunk, arms, or legs
unpleasant breath odor
unusual facial expressions
unusual tiredness or weakness
upper right stomach pain
vomiting with or without blood
yellow eyes and skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Body aches or pain
dryness of the throat
hoarseness
redness or swelling in the ear
tender, swollen glands in the neck
voice changes
Less common
Change in or loss of taste
difficulty in moving
increased appetite
joint pain or swelling
muscle pain, cramp, or stiffness
nightmares
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Levocetirizine (Xyzal Allergy) takes about 1 hour to start working, and lasts all day.
Yes, some people might feel sleepy after taking levocetirizine (Xyzal Allergy). But this medication isn't as likely to cause drowsiness compared to some other antihistamines, such as diphenhydramine (Benadryl). This is because levocetirizine (Xyzal Allergy) is a second-generation antihistamine that isn't as likely to cross into the brain compared to first-generation antihistamines. Let your primary care provider or pharmacist know if levocetirizine (Xyzal Allergy) is making you too drowsy to go about your day. They might ask you to consider other options.
Ask your primary care provider (PCP) what other allergy medication is safe for you to take along with levocetirizine (Xyzal Allergy). In general, you can take other allergy medications that work differently than levocetirizine (Xyzal Allergy). For example, if you continue to have a runny nose, your PCP might recommend a steroid nasal spray, such as fluticasone (Flonase). And if you've congestion, they might ask you to try pseudoephedrine (Sudafed) or oxymetazoline (Afrin). Of course, they'll also consider what other medical conditions you have before making a recommendation. But in general, they'll ask you to avoid taking other oral antihistamine medications with levocetirizine (Xyzal Allergy) because this raises your risk of serious side effects, like agitation or movement problems.
Each tablet of Xyzal contains 5 mg of levocetirizine. You shouldn't take 2 levocetirizine (Xyzal Allergy) tablets in 24 hours because this is higher than the dose recommended by the manufacturer and FDA for children and adults. Taking too much levocetirizine (Xyzal Allergy) can put you at risk for serious side effects, including agitation and a pounding heart. Talk with your primary care provider if your allergy symptoms aren't relieved by levocetirizine (Xyzal Allergy) alone. Depending on what symptoms you're experiencing and what other medical conditions you have, they can recommend other medications to help.
No, don't take levocetirizine (Xyzal Allergy) and diphenhydramine (Benadryl) together, unless instructed by your primary care provider. Taking two antihistamines together raises your risk of side effects, such as drowsiness, dry mouth, and dizziness. If you want to switch from levocetirizine (Xyzal Allergy) to diphenhydramine (Benadryl), start diphenhydramine (Benadryl) at least 24 hours after your last levocetirizine (Xyzal Allergy) dose.
Both levocetirizine (Xyzal Allergy) and fexofenadine (Allegra) are oral second-generation antihistamines. Both can treat symptoms of allergy and hives. But there are few differences between them. In general, levocetirizine (Xyzal Allergy) works a little quicker than fexofenadine (Allegra) to relieve symptoms. In addition, people might experience more drowsiness with levocetirizine (Xyzal Allergy) compared to fexofenadine (Allegra). Ask your pharmacist or primary care provider if you have more questions about which medication might be right for you.
Both levocetirizine (Xyzal Allergy) and cetirizine (Zyrtec) are very similar to each other because levocetirizine (Xyzal Allergy) is the active form of cetirizine (Zyrtec). They're both available as lower-cost generics, taken once per day, and have similar side effects. The biggest difference is the formulation each comes in. While both medications come as oral tablets and liquids, cetirizine (Zyrtec) also comes as chewable tablets and orally disintegrating tablets.
If you're pregnant, talk with your obstetrician about the risks and benefits of taking levocetirizine (Xyzal Allergy). This medication hasn't been well-studied in pregnancy. But in general, the American College of Obstetricians and Gynecologists (ACOG) recommends chlorpheniramine as one of the preferred antihistamines for allergy during pregnancy. Your obstetrician might only consider second-generation antihistamines, like levocetirizine (Xyzal Allergy), if the preferred options haven't worked well and only if you're already past the first trimester of pregnancy.
Levocetirizine (Xyzal Allergy) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Levocetirizine (Xyzal Allergy) can make you sleepy, which can affect your ability to focus, think, or react. This side effect might be more likely to happen or more intense if you're over 65 years old, drink alcohol while taking levocetirizine (Xyzal Allergy), or take other medications that also cause sleepiness (e.g., opioids, certain anxiety medications, sleep medications). Don't drive or operate machinery until you know how this medication affects you.
Levocetirizine (Xyzal Allergy) and other antihistamines can be found in many over-the-counter and prescription products. Taking too much levocetirizine (Xyzal Allergy) or using more than one medication containing an antihistamine (including products used on the skin) can lead to an accidental overdose and cause serious side effects, such as seizures, hallucinations, or even death.
To prevent an accidental overdose, read package labels carefully. If you're not sure if a product has an antihistamine, ask your pharmacist. Don't start any new medications while taking levocetirizine (Xyzal Allergy) without talking to your provider or pharmacist first. If you think you or your loved one has taken too much medication, get medical help right away or contact a Poison Control Center at 1-800-222-1222.
The directions can be different depending on the levocetirizine (Xyzal Allergy) product you have. Be sure to check the medication box for specific instructions or follow your provider's directions.
In general, the dose is as follows:
Tablets (over the counter (OTC) or by prescription):
Follow your prescriber's instructions if you're taking the prescription solution because the age cut-offs are different.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Levocetirizine (Xyzal Allergy) will not be safe for you to take.